A new cocrystal of pyrazinamide with oxalic acid was prepared mechanochemically and characterized by PXRD, Raman spectroscopy, solid-state NMR spectroscopy, DTA-TG, and SEM. Based on powder X-ray diffraction data the structure was solved. The formation pathway of the reaction was studied in situ using combined synchrotron PXRD and Raman spectroscopy. Using oxalic acid dihydrate the initially ne...

Riparin I is an alkamide with potential anxiolytic activity in preclinical studies. The characterization and understanding of solid-state properties play an importance role in drug development. For this work, the solid state of five riparin I batches (RIP-1, RIP-2, RIP-3, RIP-4, and RIP-5), obtained by the same synthesis process, were characterized by Scanning Electron Microscopy (SEM), Differe...

Phase identification and structure determination are important and widely used techniques in chemistry, physics and materials science. Recently, two methods for automated three-dimensional electron diffraction (ED) data collection, namely automated diffraction tomography (ADT) and rotation electron diffraction (RED), have been developed. Compared with X-ray diffraction (XRD) and two-dimensional...

Anatase phase TiO2 nanostructures (Nanoparticles and nanorods) were prepared by two different methods. The prepared samples were characterized with Powder X-ray diffraction (PXRD), Field emission scanning electron microscopy (FESEM), High resolution transmission electron microscopy (HRTEM), Brunauer-Emmett-Teller (BET) method and Barrett-Joyner-Halenda (BJH) analysis. The PXRD pattern shows tha...

The nature of Ni-hydroxide precipitates on pyrophyllite were reexamined by analytical electron microscopy (AEM), high-resolution transmission electron microscopy (HRTEM), selected-area electron diffraction (SAED), powder X-ray diffraction (PXRD), and extended X-ray absorption fine structure (EXAFS) spectroscopy. Chemical analysis of precipitates showed that the precipitate contains about 20% Al...

nanostructured ceo2 powders were synthesized via a series of hydrothermal and solution precipitation methods. three different hydrothermal methods including 1:2 and 1:1 bi:ce molar ratios at 180 °c for 48 h (s1 and s2, respectively) without calcinations and 2:1 bi:ce molar ratio at 180 °c for 48 h with calcinations (s3) were performed successfully for the synthesis of the target nanomaterials. ...

Layered solids often form thin plate-like crystals that are too small to be studied by single-crystal X-ray diffraction. Although powder X-ray diffraction (PXRD) is the conventional method for studying such solids, it has limitations because of peak broadening and peak overlapping. We have recently developed a software-based rotation electron diffraction (RED) method for automated collection an...

Fusing complex data from two disparate sources has been demonstrated to improve the accuracy in quantifying active ingredients in mixtures of pharmaceutical powders. A four-component simplex-centroid design was used to prepare blended powder mixtures of acetaminophen, caffeine, aspirin and ibuprofen. The blends were analyzed by Fourier transform infra-red spectroscopy (FTIR) and powder X-ray di...