For thousands of years, Punica granatum L. has been used in traditional medicine all over the world and predate the introduction of antibacterial drugs. The aim of the present study was to investigate the antibacterial activity of aqueous and ethanolic extracts of Punica granatum L. bark obtained by decoction and maceration. The different extracts of Punica granatum L. (Lythraceae) bark have be...

In our previous studies, we showed the inhibitory effects of Punica granatum L. flower and Rhus coriaria L. fruit water extracts on dental plaque accumulation by several bacteria, especially Streptococcus mutans (S. mutans), on orthodontic wire by in-vitro assays. In this study, the anti-cariogenic properties of the extracts were evaluated by assessing their effects on expression of glycosyltra...

The antidiarrheal effects of the aqueous extract of Punica granatum L. (Punicaceae) peels were evaluated in rats. Studies were carried out on the isolated rat ileum, gastrointestinal motility in vivo, and on castor oil–induced diarrhea in rats. The results revealed that the extract exhibited a concentration-dependent inhibition of the spontaneous movement of the isolated rat ileum and attenuate...

Dementia is one of the age related mental problems and characteristic symptom of various neurodegenerative diseases including Alzheimer's disease. This impairment probably is due to the vulnerability of the brain cells to increased oxidative stress during aging process. Many studies have shown that certain phenolic antioxidants attenuate neuronal cell death induced by oxidative stress. The pres...

The present study has been designed to explore the beneficial effect of Punica grantum leaves in experimental cardiac hypertrophy in rats. Punica granatum L., (Family: Punicaceae) is used in Indian Unani medicine for treatment of diabetes mellitus, cytotoxixity and in wound healing owing to its antioxidant activity. The male wistar rats were anaesthetized with thiopentone sodium and were subjec...

Pomegranate is a native Persian fruit that is grown around the world; the present study is the report of the research on different extracts of different polarity from flowers regarding their antioxidant activity. Punica granatum L. var. Isfahan Malas flowers were extracted with petroleum ether. The dried petroleum extract was suspended in ethanol %80 and successively partitioned with n-butanol....

TAMAE YODA,1 LARRY I. CRAWSHAW,2 KYOKO YOSHIDA,1 LIU SU,1 TAKAYOSHI HOSONO,2 OSAMU SHIDO,3 SOTARO SAKURADA,3 YUTAKA FUKUDA,1 AND KAZUYUKI KANOSUE2 1Department of Physiology and Biosignalling, Graduate School of Medicine, Osaka University, Osaka; 2Department of Physiology, School of Allied Health Sciences, Osaka University Faculty of Medicine, Osaka 565-0871; and 3Department of Physiology, Schoo...

BACKGROUND Rind of Punica granatum is traditionally used in treatment of abdominal cramps and various GIT disorders. So far spasmolytic activity of rind of Punica granatum has been reported using in vitro model. However, its mode of action is not explored yet. Therefore, the current work describes the possible mode of action for spasmolytic activity of methanolic extract of rind of Punica grana...

The ethnobotanical survey conducted in this study showed that 21 plant species belonging to 14 families are used in traditional medical practice in Limpopo Province, South Africa, for the treatment of diarrhoea. Methanol, ethanol, acetone and hot water extract from different plant parts (leaves, roots, bark and stem rhizome), of several of these plants (Indigofera daleoides, Punica granatum, Sy...