BACKGROUND Systematic lymph node dissection is not routinely performed in patients undergoing pulmonary metastasectomy (PM) of colorectal cancer. The aim of the study was to identify risk factors for lymph node metastases (LNM) and to determine prognosticators for survival in colorectal cancer patients with pulmonary metastases. METHODS We retrospectively reviewed our prospective database of ...

Introduction Pulmonary metastases are the commonest sites of distant metastases in osteosarcoma. Although cytotoxic chemotherapy after primary surgical treatment of limb osteosarcoma is used widely in an attempt to eradicate micro-metastases, hopes of cure once clinically evident metastases are present are limited. However, long survivals have been reported following resection of pulmonary meta...

BACKGROUND The presence of multiple metastatic pulmonary nodules is a predictor of poor survival after pulmonary metastasectomy. However, there is a paucity of data addressing the exact number of pulmonary metastases over which prognosis becomes grave. The aim of our study is to investigate the prognosis of pulmonary metastasectomy from colorectal cancer (CRC) depending on the number of pulmona...

CONTEXT Data from a large cohort of patients with pulmonary metastases from differentiated thyroid cancer (DTC) were retrospectively analyzed. OBJECTIVE To assess the effect of radioiodine therapy and investigate the prognostic factors of survival for patients with pulmonary metastasis secondary to DTC. METHODS A total of 372 patients with pulmonary metastasis from DTC treated with (131)I e...

Stimulated by the clinical impression tha t some patients show rapid development of distant metastases for the first time shortly following surgical or irradiation treatment of their primary tumor, the surgical service of the National Cancer Institute has undertaken a series of experiments dealing with the effect of surgical excision or local irradiation of a transplantable mouse tumor on the d...

OBJECTIVE To analyze the benefits and prognostic factors after surgical resection of pulmonary metastases from colorectal cancer (CRC). METHODS From Jan. 2004 to Jan. 2015, continuous 88 cases diagnosed with pulmonary metastases from CRC, including 15 cases of synchronous metastases and 73 metachronous metastases, were analyzed in the retrospective study. RESULTS All of these 88 cases under...

BACKGROUND Due to local ventilation and perfusion differences in the pulmonary lobes, the microenvironmental influence on metastasis formation in the lung can be studied. We, therefore, investigated whether the anatomical distribution of first lung metastases follow a particular pattern. MATERIALS AND METHODS Thirty-three out of 273 patients with melanoma who underwent 18F-fluorodeoxyglucose ...

BACKGROUND We reviewed resection of pulmonary metastases preformed by the Department of Thoracic Surgery at Kyoto University Hospital to confirm the clinical significance of this surgery in patients with colorectal carcinoma and a history of hepatic metastasis. METHODS From 1992 to 2006, 19 patients with colorectal carcinoma and a history of hepatic metastasis underwent a pulmonary metastasec...

From a clinician’s viewpoint, carcinomatous pulmonary metastases are still discouraging entities. With the remarkable strides in producing regressive changes of metastatic breast and prostatic carcinoma with hormonal therapy, and the ever widening vista of therapeutic results with artificial radioactive substances, it behooves all of us to re-examine our fundamental knowledge of pulmonary metas...