background: one-third of the world’s population is currently infected by tubercle bacillus. this study was performed to evaluate epidemiological and clinical aspects of confirmed cases of tuberculosis infections in a seven-year time period, between years of 2002 to 2008, in the city of hamadan, west of iran. materials and methods: in this descriptive retrospective study, medical records of 375 ...

background: several studies have showed an increased prevalence of airflow obstruction in first degree relatives of individuals with chronic obstructive pulmonary disease (copd). considering no specific research had evaluated airway resistance in offspring of patients with severe copd, we utilized a spirometry and a impulse oscillometry (io) to evaluate this population. materials and methods: i...

objective(s): gastroesophageal reflux disease (gerd) is one of the most common digestive disorders that frequently lead to pulmonary complications due to gastric fluid aspiration. in the present experimental study, chronic aspiration of gastric fluid, its components and bile salts in rat lung was performed to find out the main factor(s) causing pulmonary complications of gastric fluid aspiratio...

conclusions pressure support ventilation, but not spontaneous breathing, induces a significant redistribution of ventilation towards the ventral region. the sensitivity of the support trigger appears to influence the distribution of ventilation only during the early phase of inspiration. background in supine position, pressure support ventilation causes a redistribution of ventilation towards t...

a2-year-old cachectic cross-breed gelding was admitted toveterinary teaching hospital of university of tehran followingthe onset of a marked respiratory distress, coughing and ventraledema. clinical examinations indicated harsh respiratory andexpiratory sounds as well as jugular vein distention. therespiratory and heart rates were 35/min and 60 bpm, respectively.agrade iii/iv pansystolic murmur...

conclusions we observed acceptable results regarding both efficacy and safety with 62.5 mg of bosentan, twice daily in this group of patients. further clinical trials investigating pah with lower dosages of bosentan may be warranted. results no adverse drug reaction was observed during the follow-up. clinical worsening occurred in six (14%) patients, at least one year after treatment, two of th...

background:  pericardial effusion (pe) in down syndrome (ds) patients  usually occur s   secondary to hypothyroidism,  but  we have   no  report of massive pericardial effusion in   euthyroid   down syndrome patient with  supravalvar  pulmonary stenosis . case presentation:  we  report ed   an   11-month-old  male with down syndrome   with  massive  pericardial  effusion that  had conservative ...

background : there is little evidence about the role of zafirlukast (a highly selective ltd4 antagonist) in chronic obstructive pulmonary disease (copd). the zafirlukast can reduce the need for short-acting rescue β2 agonists, produce fewer exacerbations of asthma and increased quality of life as possible benefits treatment for asthma. the aim of our study was to evaluate the effects of zafirlu...

conclusions although we found a trend towards decreasing spah and improving 6mwd, no statistically significant shift were detected in our outcomes due to inadequate sample size. patients and methods a registered (irct201108257411n1), triple-blind, randomized controlled trial was performed in rasoule akram hospital, tehran, from 2009 to 2011. forty five patients with secondary pulmonary hyperten...

background: hyponatremia has poor outcomes in other cardiopulmonary disorders, but its predictive value in predicting mortality of patients with acute pulmonary embolism is unknown. so, we evaluate the mortality of inpatients diagnosed with pulmonary embolism (pe) who had hyponatremia at the time of admission. materials and methods: by conducting a cohort study in patients with acute pulmonary ...