background: the aim of this study was to determine the th1 and th2 serum cytokines, in patients with psoriasis and to com pare their cytokine levels with those of normal control subjects. methods: serum levels of interferon-gamma (ifn-γ), interleukin-2 (il-2), interleukin-4 (il-4), and interleukin-10 (il-10) were measured by enzyme linked immunosorbent assay in 40 patients with psoriasis and in...

objective: psoriasis is a chronic inflammatory disease. it may cause poor quality of life. the purpose of this study was to determine the prevalence of insulin resistance in patients with psoriasis to clarify the relationship between insulin resistance and psoriasis. materials and methods: this case-control study was conducted on 110 patients with psoriasis and 110 healthy people. fasting serum...

Background: Psoriasis is a chronic disease that may affect patients’ quality of life. We investigated the quality of life (QoL) and its related factors in psoriasis patients. Methods: In this cross-sectional study, 123 patients with psoriasis vulgaris were enrolled, who were at the age of 18-55 years. The QoL was assessed by the psoriasis disability index (PDI...

Introduction: Psoriasis is a chronic inflammatory skin disease characterized by plaques covered with silvery scales. Psoriasis is highly prevalent in different countries in the world, including Iran. Several studies have reported a significant association between psoriasis and cardiovascular diseases. This study aimed to evaluate the relationship between psoriasis and cardiac disease using echo...

Psoriasis is a chronic, genetically determined skin disease. A variety of biochemical and molecular biological alterations have been identified, but the pathogenesis of psoriasis is still not clear. For patients with mild to moderate psoriasis, topical therapies are generally used. However, approximately one-third of the patients have a moderate to severe psoriasis and need a systemic therapy. ...

Background: The aggravating role of Staphylococcus aureus is well known in atopic dermatitis but has not yet been proven in psoriasis. The role of Staphylococcus aureus superantigens is emphasized in the initiation, maintenance and complications of psoriasis. We investigated the frequency of nasal, axillary, and perineal carriage of Staphylococcus aureus (SA) in patients with psoriasis and its ...

Background: Psoriasis is a prevalent chronic T cell mediated inflammatory skin disorder. Recent studies have reported an increase in the incidence of arrhythmia in psoriasis patients who run an excessive risk of metabolic syndrome and cardiovascular diseases. P-wave dispersion (PWD) and duration are important electrocardiographic (ECG) markers employed to anticipate the risk of atrial arrhythmi...

psoriasis is an autoimmune and recurrent chronic inflammatory skin disease. about 1-3% of the world wide populations are affected. the characteristic features are hyperprolifration of keratinocytes leading to redness, thickening and scaling of epidermis followed with itching and appearance of the lesions which in most cases bother the patients medically and psychologically. psoriasis is symptom...

generalized pustular psoriasis with hypoparathyroidism has been reported previously often as a post thyroidectomy syndrome with hypoalbuminemia and hypocalcemia. but reports on association of pustular psoriasis with idiopathic hypoparathyroidism are very rare, and almost all of them occurred in patients with known psoriasis vulgaris. we report one of the youngest cases of this association in a ...