Adrenocortical tumors (ACTs) are extremely rare in infants. Pediatric ACTs are therapeutic and diagnostic challenge because histological criteria for distinguishing benign from malignant tumors seen in adults are not always reliable in children .The aim of this report was to present clinical features, hormonal profile, and histopathological characteristics of an infant with Adrenal tumors. A...

Ovarian tumours are rare in children and account for approximately 1% of all the tumours of childhood (Schultz, 1926). The majority are benign, the commonest being cystic teratoma. Tumours causing sexual precocity and pseudoprecocity are particularly rare; Wilkins (1957), in a long experience of paediatric endocrinology, personally encountered only one case. The ovarian tumour most often respon...

Sexual precocity is considered to be present when indications of genital maturation become apparent in boys before the age of 10 years and in girls before the age of 8 years (Seckel, 1946). It is customary to divide these cases into two groups. In those with true precocious puberty maturation with spermatogenesis or ovulation has occurred in a normal manner, but at an abnormally early age; in t...

Sexual precocity is considered to be present when indications of genital maturation become apparent in boys before the age of 10 years and in girls before the age of 8 years (Seckel, 1946). It is customary to divide these cases into two groups. In those with true precocious puberty maturation with spermatogenesis or ovulation has occurred in a normal manner, but at an abnormally early age; in t...

Steroid cell tumor, not otherwise specified (NOS), are rare ovarian tumor, in addition, it is more rare in children. The majority of these tumors produce several steroid hormones, particularly testosterone. Estrogen also secreted by steroid cell tumor, NOS, but it is uncommon. Furthermore, hypertension is an infrequent sign in steroid cell tumor, NOS. An 8.5-yr-old girl with hypertension and fr...

Peutz Jeghers syndrome ( PJ S ) is an autosomal dominant disease that combines hamartomatous polyposis ,a periorificial lentiginose and a high risk of associated cancers. We report the observation of a girl 07 years old of personal historyof acute intestinal intussusception occurred a year ago who consults for signs of early puberty and the onset of vaginal bleeding up to 06 months . The child ...