BACKGROUND Stem cell transplantation has been investigated for repairing damaged tissues in various injury models. Monitoring the safety and fate of transplanted cells using noninvasive methods is important to advance this technique into clinical applications. METHODS In this study, lower-limb ischemia models were generated in nude mice by femoral artery ligation. As negative-contrast agents,...

This paper reported the fabrication of a multifunctional nanoplatform by modifying hollow Prussian blue nanoparticles with hyaluronic acid grafting polyethylene glycol, followed by loading 10-hydroxycamptothecin for tumor-targeted thermochemotherapy. It was found that the surface modification of hollow Prussian blue nanoparticles with hyaluronic acid grafting polyethylene endowed a great colloi...

The use of a viral template has allowed the synthesis of monodisperse Prussian blue nanoparticles with a diameter of 18 +/- 1.7 nm and their organization into hexagonal patterns on mica and hydrophilic carbon surfaces.

Prussian blue nanoparticles were explored for the first time as an excellent contrast agent for enhancing photoacoustic tomography in vitro and in vivo due to their superior absorption efficiency of near-infrared laser pulses at a wavelength of 765 nm.

Dispersible, nearly isolated 6 nm nanoparticles of the CsNiCr(CN)6 Prussian blue analogue coated with polyvinylpyrrolidone (PVP) show superparamagnetic behaviour with a relatively high blocking temperature TB = 9 K.

Aim Silver nanoparticles have long been used as potent antibacterial agents. However, toxicity concerns of silver nanoparticles have limited their successful clinical applications. Hence, development of silver-based novel biocompatible nanomaterials for antibacterial applications is a challenging task. Materials & methods Accordingly, in this work, we synthesized a biocompatible silver-based ...

Conjugation of monoclonal antibodies to super paramagnetic nanoparticles is an effective method for cancer diagnosis and treatment. In this study the humanized anti her2/neu monoclonal antibody- Herceptin- was conjugated to super paramagnetic iron oxide (SPIO) nanoparticles using EDC method. The concentration of the conjugated antibodies was measured by Bradford assay. The antibody-nanoparticle...

A CoFe Prussian blue analogue is coupled with brown TiO2 nanoparticles to achieve an earth-abundant photocatalytic water oxidation assembly.

Development of multifunctional nanoparticles that selectively target to human tumors for in vivo tumor imaging as well as inhibition of tumor growth holds a great promise for improving survival rate of cancer patients. In this study, we have engineered peptide conjugated superparamagnetic iron oxide (SPIO) nanoparticles targeting to urokinase plasminogen activator receptor (uPAR) or a single ch...