background: gel polymers are considered as new dosimeters for determining radiotherapy dose distribution in three dimensions. objective: the ability of a new formulation of magic-f polymer gel was assessed by experimental measurement and monte carlo (mc) method for studying the effect of gold nanoparticles (gnps) in prostate dose distributions under the internal ir-192 and external 18mv radioth...

Background: Gel polymers are considered as new dosimeters for determining radiotherapy dose distribution in three dimensions.Objective: The ability of a new formulation of MAGIC-f polymer gel was assessed by experimental measurement and Monte Carlo (MC) method for studying the effect of gold nanoparticles (GNPs) in prostate dose distributions under the internal Ir-192 and external 18MV radiothe...

background: stereotactic body radiotherapy (sbrt) has emerged as an effective treatment for localized prostate cancer. however, prostate-specific antigen (psa) kinetics after sbrt has not been well characterized. the objective of the current study is to analyze the rate of psa decline and psa nadir following hypofractonated sbrt in localized prostate cancer. materials and methods: from 2008 to ...

The immune checkpoint inhibitor (ICI) is a promising strategy for treating cancer. However, the efficiency of ICI monotherapy limited, which could be mainly attributed to tumor microenvironment “cold” tumor. Prostate cancer, type most common cancer affecting men’s health. Radiotherapy regarded as one effective prostate treatments. In era therapy, enhanced antigen presentation and cell infiltrat...

Craniofacial skeletal metastasis is a rare presentation of advanced prostate cancer. This is a report of a 69-year-old man who presented with numbness of the right lower lip and recently ill-fitting lower denture. Based on the medical history of benign prostate hyperplasia (BPH) and suspicion of a metastatic tumor, prostate core needle biopsy was performed. Histology of the prostate biopsy con...

Background: Intensity-modulated radiotherapy (IMRT) is one of the most usable methods in prostate radiotherapy that is used with different techniques. The aim of this study was to evaluate and compare the dosimetric and radiobiological effects of prostate IMRT techniques regarding to joint volume between the target tissue and organs at risk as a patients anatomical parameter. Methods: This res...

Introduction: The accuracy of the patient setup and tumor location are major factors that determine the efficacy of radiotherapy treatment planning. In the prostate radiotherapy, reproducibility of the prostate location for each treatment fraction is problematic owing to varying filling of the rectum and bladder. According to this, the aim of this study was to measure the inte...

PURPOSE Early salvage radiotherapy following radical prostatectomy for prostate cancer is commonly advocated in place of adjuvant radiotherapy. We aimed to determine the optimal definition of early salvage radiotherapy. MATERIALS AND METHODS We performed a multi-institutional retrospective study of 657 men who underwent salvage radiotherapy between 1986 and 2013. Two comparisons were made to ...

background: to analyze the dosimetric and radio biologic advantages between intensity modulated radiotherapy (imrt) and 3 dimensional conformal radiotherapy (3dcrt) and selection of optimal photon energy for imrt treatments. material and methods: 24 patients with localized prostate carcinoma were planned for 3dcrt and imrt techniques. radiation dose of 54 gy with 2 gy/fraction, was planned to p...

[2] Trock BJ, Han M, Freedland SJ, et al. Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after radical prostatectomy. JAMA2008;299: 2760–9. [3] Stephenson AJ, Shariat SF, Zelefsky MJ, et al. Salvage radiotherapy for recurrent prostate cancer after radical prostatectomy. JAMA 2004; 291:1325–32. [4] Thompson IM, Tangen CM, Parade...