Objective- To compare transabdominal (TA) and transrectal (TR) ultrasonography of the prostate gland. Design- Experimental study. Animals- 10 intact male dogs that required euthanasia for reasons other than prostatic disease. Procedures- Prostatic length (L), width (W) and height (H) were measured in T A (L1, W1 and H1) and TR (L2 and H2...

background: there is yet a dearth of literature on the antifertility effect of momordica charantia on the male reproductive system. the aim of this study was to determine the effect of graded oral doses of methanolic seed extract of momordica charantia on the histology of prostate gland and seminiferous tubules of rats. methods: forty male sprague-dawley rats, weighing 176±7 g were assigned ran...

The adult prostate gland grows and develops under hormonal control while its physiological functions are controlled by the autonomic nervous system. The prostate gland receives sympathetic input via the hypogastric nerve and parasympathetic input via the pelvic nerve. In addition, the hypogastric and pelvic nerves also provide sensory inputs to the gland. This review provides a summary of the i...

Primary squamous cell carcinoma is an uncommon tumor of the prostate gland. We report a 77-year-old male patient with urinary frequency and constipation. Fine needle biopsy from prostate was suspicious of squamous cell carcinoma of the prostate. Whole body positron emission tomography/computed tomography scan revealed high fluorodeoxyglucose uptake in prostate gland. Transurethral resection con...

Introduction: Benign Hyperplasia of the Prostate (BHP) and prostate cancer comprise about 90% all diseases gland. An increase in serum Specific Antigen (PSA) is an indicator underlying hyperplasia, inflammation, or cancer. Mast cells are found both inflamed tumour tissue. Aim: To find correlation mast cell count with age, weight prostate, PSA level, thereby distinguishing between benign inflamm...

The growth of the prostate gland is androgen-dependent. Testosterone is converted to the most potent dihydrotestosterone (DHT) by 5alpha-reductase within the prostate. Androgen interacts with androgen receptors (AR) to regulate normal growth of the prostate and has also been implicated in both the progression of benign prostate hyperplasia and prostate cancer. This study was conducted to compar...

Numerous mouse models of prostate carcinogenesis have been developed, but hitherto there has been no model in which the prostate gland could be imaged in live animals. The transgenic model generated here targeted mouse prostate gland using a firefly luciferase enzyme under the control of a small but highly active and specific supra prostate-specific antigen (sPSA) promoter. We evaluated postnat...

Background: Diffusion-weighted imaging (DWI) is a main component of multiparametric MRI for prostate cancer detection. Recently, high b value DWI has gained more attention because of its capability for tumor characterization. Objective: To assess based on histopathological findings of transrectal ultrasound (TRUS)-guided prostate biopsy as a reference, an...

The Prostate, which is part of the male reproductive system, is an exocrine gland that encloses the male urethra and its base is located at the bladder neck. A thin layer of connective tissue separates the prostate and seminal vesicles from the rectum posteriorly. There are three distinct zones found in the prostate gland. These are (a) the peripheral zone, (b) the transitional zone and (c) the...

PURPOSE We aimed to evaluate the efficacy of magnetic resonance imaging (MRI)-directed cognitive fusion transrectal ultrasonography (TRUS)-guided anterior prostate biopsy for diagnosis of anterior prostate tumors and to illustrate this technique. METHODS A total of 39 patients with previous negative TRUS biopsy, but high clinical suspicion of occult prostate cancer, prospectively underwent pr...