OBJECTIVE There is considerable variation in practice regarding the use of prophylactic antibiotic therapy in spinal operations. To date, individual studies have not demonstrated a significant benefit for prophylactic antibiotic therapy in spinal operations. METHODS Systematic database searches for randomized prospective trials of prophylactic antibiotic therapy in spinal surgery, general neu...

OBJECTIVE Evaluate the effectiveness of variation of prophylactic antibiotic in laparoscopic cholecystectomy. MATERIAL AND METHOD A retrospective data review was undertaken of patients who received a laparoscopic cholecystectomy between January 1, 2005 and December 31, 2008 in Songklanagarind Hospital. The prevalence of surgical site infection (SSI), the variation of antibiotic prescription, ...

background : the use of antibiotic prior to surgery is widely accepted. the who has recommended the use of atc/ddd (anatomical therapeutic chemical / defined daily dose) for the analysis of drug utilization.the aims of the present study are 1) to analyze the assessment of prophylactic antibiotic usage prior to surgery, 2) to assess the drug administration based on antibiograms and 3) to compare...

The aim of the study was to compare the resistance patterns of Escherichia coli isolates from pig herds with or without prophylactic use of anti-microbial substances. The presented pig units received either antibiotics or oregano as preventive feed additives. The trial was performed from April to October 2001, in the large 'country-corner', Hungary-Rumania-Serbia. Thirty of 39 evaluated herds s...

OBJECTIVE The effect of prophylactic antibiotic treatment on infection and survival of acute necrotizing pancreatitis (ANP) remains uncertain. The aim of this study was to assess the long-term efficacy of prophylactic antibiotic treatment for ANP. MATERIAL AND METHODS Searches were carried out of electronic databases including Medline, EMBASE, the Cochrane Controlled Trials Register, the Scie...

BACKGROUND In this study we investigated changes in the status of antibiotic use in Tianjin since the implementation of the Antibiotic Stewardship Program (ASP) (2011-2013), as well as existing problems, strategies, and outcomes to promote rational clinical antibiotic use. MATERIAL AND METHODS A quasi-experimental study was performed to investigate situations of antibiotic use in secondary and ...

Methods Prophylactic antibiotic prescriptions for patients undergoing surgery in January 2011 were extracted from the medical records. Variables collected included: surgical procedure, prophylactic antibiotic prescribed (ATC code), surgery classification (clean, clean contaminated, contaminated and dirty), and prophylaxis duration. A descriptive statistical analysis and cross-tabulations (chisq...

  Background : The use of antibiotic prior to surgery is widely accepted. The WHO has recommended the use of ATC/DDD (Anatomical Therapeutic Chemical / Defined Daily Dose) for the analysis of drug utilization.The aims of the present study are 1) to analyze the assessment of prophylactic antibiotic usage prior to surgery, 2) to assess the drug administration based on antibiograms and 3) to compa...