The ventral pelvic skin of the tree frog Hyla japonica expresses two kinds of arginine vasotocin (AVT)-stimulated aquaporins (AQP-h2 and AQP-h3), which affect the capacity of the frog's skin to absorb water. As such, it can be used as a model system for analyzing the molecular mechanisms of water permeability. We investigated AQP dynamics and water permeability in the pelvic skin of H. japonica...

This paper reports on a recent study aimed at developing the stress-induced magnetic anisotropy (SMA) technique for characterizing residual stresses in case hardened steel components. The results of SMA measurements performed on flat induction hardened steel discs with different case depths confirm the feasibility of detecting principal stress axes by measuring the angular variation of magnetic...

Previous work has shown that undissociated forms of organic acids, such as formic, acetic, and propionic acids, increase the permeability of barley roots to ions. The work here was undertaken to test whether these undissociated acids affect the lipids from the root membranes in such a way as to account for the permeability increase. Relative amounts of the principal fatty acids from barley root...

Hillslope scale runoff is generated as a result of interacting factors that include water influx rate, surface and subsurface properties, and antecedent saturation. Heterogeneity of these factors affects the existence and characteristics of runoff. This heterogeneity becomes an increasingly relevant consideration as hydrologic models are extended and employed to capture greater detail in runoff...

Biliary excretion (BE) is a major elimination pathway, and its prediction is particularly important for optimization of systemic and/or target-site exposure of new molecular entities. The objective is to characterize the physicochemical space associated with hepatobiliary transport and rat BE and to develop in silico models. BE of 123 in-house compounds was obtained using the bile-duct cannulat...

The site and character of precious and basemetal epithermal deposits is determined by several principal factors which include: structure, stratigraphy, lithology, pressure and temperature. hydrology, chemistry of the mineralizing fluid, and syn-hydrothermal development of permeability or changes in hydraulic gradient (White and Hedenquist, 1990). This study investigates the syn-hydrothermal dev...

A model function relating effective stress to fracture permeability is developed from Hooke's law, implemented in the tensorial form of Darcy's law, and used to evaluate discharge rates and pressure distributions at regional scales. The model takes into account elastic and statistical fracture parameters, and is able to simulate real stress-dependent permeabilities from laboratory to field stud...

Apple cider, with (0.1%) and without potassium sorbate, was packaged in 3 different materials to evaluate the effects of irradiation (2 kGy) and storage on flavor. Irradiated apple cider samples were compared with unirradiated samples stored in glass jars. Volatile flavor compounds, soluble solids, and titratable acidity were determined weekly throughout 3 wk of refrigerated storage. Oxygen per...

The Density Functional Theory (DFT) method and the 6-31G** basis set were employed to calculate the molecular properties of artemisinin and 20 derivatives with different degrees of cytotoxicity against the human hepatocellular carcinoma HepG2 line. Principal component analysis (PCA) and hierarchical cluster analysis (HCA) were employed to select the most important descriptors related to antican...

Recording of glutamate-activated currents in membrane patches was combined with RT-PCR-mediated AMPA receptor (AMPAR) subunit mRNA analysis in single identified cells of rat brain slices. Analysis of AMPARs in principal neurons and interneurons of hippocampus and neocortex and in auditory relay neurons and Bergmann glial cells indicates that the GluR-B subunit in its flip version determines for...