The universal definition of glaucoma is that it is an optic neuropathy with assorted etiology, which disturbs the optic nerve head, thereby resulting in visual loss and permanent impairment of visual function [2]. On the other hand, primary open angle glaucoma is an optic neuropathy that is commonly associated with increased intraocular pressure. High intraocular pressure leads to retinal gangl...

objective: hydrostatic pressure is crucial component of cell environment and fundamental physical quantity, also it is the main factor of both cell integrity and function. pressure variation disorder, beyond physiological limits, may lead to pathological states. in this study, we examined the effect of hydrostatic pressure on apoptosis induction, viability, morphology, adhesion potency to subst...

PURPOSE To evaluate the technique, safety, and efficacy of the retropupillary implantation of iris-claw intraocular lenses in a long-term follow-up study. PATIENTS AND METHODS This retrospective study included 31 eyes of 31 patients who underwent an Artisan aphakic intraocular lens implantation between January 2006 and February 2011 at the University Hospital Essen, Essen, Germany and at the ...

Elevated intraocular pressure may lead to retinal ganglion cell injury and consequent visual deficits. Chronic intraocular pressure increase is a major risk factor for glaucoma, a leading blinding disease, and permanent visual deficits can also occur following acute pressure increments due to trauma, acute glaucoma or refractive surgery. How pressure affects retinal neurons is not firmly establ...

glaucoma is the second leading cause of irreversible blindness and a neurodegenerative disease with a complex pathogenesis. increasing evidence suggests that oxidative stress and mitochondrial dysfunction have crucial roles in most neurodegenerative diseases such as glaucoma. the conventional clinical treatment for glaucoma is lowering the intraocular pressure (iop). some patients have normal i...

METHODS: Retrospective analysis of data from patients who underwent toric iris-fi xated pIOL (Artifl ex® and Artisan®) implantation in Centro Hospitalar Lisboa Central between 2009 and 2013. Th e main parameters evaluated were best corrected visual acuity (BCVA), uncorrected visual acuity (UCVA), manifest refraction, intraocular pressure (IOP), central endothelial cell count (ECC) and complicat...

purpose: to report a case of spinal cord tumor with visual symptoms and papilledema due to increased intracranial pressure. patient and findings: a 24-year-old woman was referred because of recent blurred vision in both eyes. visual acuity was 20/25 and 20/20 in the right and left eyes, respectively. fundoscopy revealed bilateral papilledema. other ophthalmic examinations were normal. visual fi...

Background: Many physical and mechanical phenomena occur during the acupuncture and tuina regime, and pressure is one of the most basic mechanical phenomena. Objectives: To understand the cellular bio-physical mechanism of basic mechanical stimulation via acupuncture and tuina by investigating the effect of different in vitro pressures on the cel...