OBJECTIVE A population-based survey was conducted in 1999 to describe the patterns of migraine diagnosis and medication use in a representative sample of the US population and to compare results with a methodologically identical study conducted 10 years earlier. METHODS A survey mailed to a panel of 20 000 US households identified 3577 individuals with severe headache meeting a case definitio...

OBJECTIVE To provide a teratology update for prescription and non-prescription drugs and infections during pregnancy. OPTIONS Limited to teratology principles and possible common exposures during pregnancy. EVIDENCE A search of Medline and textbooks was conducted for information published to June 2006 on teratology exposure risks. This document represents an abstraction of the information. ...

OBJECTIVE To characterize the types of comparators and endpoints used in efficacy trials for approvals of supplemental indications, compared with the data supporting these drugs' originally approved indications. DESIGN Systematic review. SETTING Publicly accessible data on supplemental indications approved by the US Food and Drug Administration from 2005 to 2014. MAIN OUTCOME MEASURES Typ...

harmaceutical prices have risen draP l matically in the past 10 years and will I continue to escalate for the next two or three years, Michael Pollard told participants at Managing the Rising Cost of Drugs : A Mult idiscipl inary Approach to Improving Hospital Services, a November 1991 meeting held in Westborough, MA. Pollard, long-time pharmaceutical analyst and partner at the Washington, DC, ...

A survey was carried out among patent medicine dealers to evaluate their practices that militate against laws governing prescriptions-only medicines in Nigeria. Questionnaires were distributed to 46 patent medicine dealers and later collected from them on appointment. Analysis of the results showed that all the patent medicine dealers were aware of the law governing the sale of prescription dru...