surgery for heart diseases during pregnancy, especially necessitating cardiopulmonary bypass, is believed to trigger maternal and fetal risks and should be performed only when medical therapy has been unsuccessful to alleviate the cardiac decompensation. a 33-year-old pregnant woman in her 33rd week of gestation was admitted to our hospital. she had rheumatic mitral valvular stenosis and had un...

conclusions moderate ppm has no negative effect on echocardiographic trans-aortic pressure gradients or the patients’ nyha functional status after avr with a carbomedics prosthesis in the mid-term follow up. results of the 66 studied patients, 39 were male and 27 were female. the mean age of the patients was 43 ± 17 with a range of 6 - 76 years. implanted sizes of the carbomedics av prosthesis ...

BACKGROUND Advances in surgical technique, prosthetic heart valve design, and anticoagulation have contributed to an overall improvement in morbidity and mortality in women with heart valve prostheses as well as increased feasibility of pregnancy. Previous work investigating the pregnancies of women with prosthetic valves has been directed largely toward understanding the influence of anticoagu...

year: the lowest in the youngest age group and the highest in the oldest. Intracranial haemorrhage was seen at an unacceptable rate (0.6–0.7/year) in all age groups. Therefore, the authors conclude that the use of mechanical AVR below the age of 60 years is associated with a similar rate of intracranial bleeding as seen in older patients. This report shows the deleterious effect of over-anticoa...

introduction: rheumatic heart disease still remains one of the leading causes of congestive heart failure and death owing to valvular pathologies, in developing countries. valve replacement still remains the treatment of choice in such patients.the aim of this study wasto analyze the postoperative outcome of  double valve replacement (mitral and aortic ) in patients of rheumatic heart disease. ...

OBJECTIVE To evaluate the outcome of pregnancy in women with mechanical heart valve prostheses in relation to the anticoagulant treatment used in the first trimester and the incidence of thrombotic and bleeding complications. METHODS 92 pregnancies in 59 women were followed between 1986 and 1997. In 31 pregnancies, oral anticoagulants were discontinued when pregnancy was diagnosed and subcuta...

Introduction: Rheumatic heart disease still remains one of the leading causes of congestive heart failure and death owing to valvular pathologies, in developing countries. Valve replacement still remains the treatment of choice in such patients.The aim of this study wasto analyze the postoperative outcome of  double valve replacement (Mitral and Aortic ) in patients of rheumatic heart disease. ...

BACKGROUND The problem of prosthetic heart valve selection in fertile women with acquired heart defects remains crucial in modern cardiology. Mechanical heart valves require lifelong indirect anticoagulant therapy, which has significant fetal toxicity and is unacceptable for women planning pregnancy. Bioprosthetic heart valves are the best choice for fertile women; however, their durability is ...

We describe two patients with Starr-Edwards mitral valve replacements who underwent pregnancy on oral anticoagulants and who were successfully delivered of live babies. The literature on pregnancy with prosthetic heart valves is reviewed. It is suggested that properly controlled oral anticoagulation should be continued until the onset of labour; the anticoagulant effect should then be reversed ...

BACKGROUND Patients undergoing heart-valve replacement may receive a mechanical prosthesis, necessitating lifelong anticoagulant treatment, or a porcine bioprosthesis, which involves no absolute need for anticoagulants. METHODS We carried out a randomized, prospective trial to compare the durability of the Bjork-Shiley mechanical prosthesis (spherical tilting-disk model) and the incidence of ...