AIM The measurement of progesterone receptors (PR) is recommended as part of the clinical management of breast and endometrial cancers, and immunohistochemistry on formalin fixed tissue is now the method of choice. PR is expressed as two isoforms, PRA and PRB, and although both these proteins are expressed in hormone dependent cancers, there is evidence that a large proportion of tumours expres...

The most important goal of this study is to enhance our understanding of the crucial functional relationships that determine the behavior of the systemic circulation and its underlying physiological regulatory mechanisms with minimal modeling. To the present day, much has been said about the indirect hydraulic effects of right atrial pressure (PRA) via cardiac output (CO) on arterial pressure (...

The identification of mycobacteria is essential because tuberculosis (TB) and mycobacteriosis are clinically indistinguishable and require different therapeutic regimens. The traditional phenotypic method is time consuming and may last up to 60 days. Indeed, rapid, affordable, specific and easy-to-perform identification methods are needed. We have previously described a polymerase chain reactio...

OBJECTIVES To explore and understand the experiences and priorities of pregnant women living with fears and worries related to fetal/infant and maternal health, the birthing process and ability to parent the infant (ie, pregnancy-related anxiety (PRA)) in Mwanza, Tanzania. DESIGN Descriptive phenomenological approach. SETTING Two clinics in the Ilemela and Nyamagana districts of Mwanza. P...

More than 70 species of mycobacteria have been defined, and some can cause disease in humans, especially in immunocompromised patients. Species identification in most clinical laboratories is based on phenotypic characteristics and biochemical tests and final results are obtained only after two to four weeks. Quick identification methods, by reducing time for diagnosis, could expedite instituti...

Objective(s): Protosappanin A (PrA) is an effective and major ingredient of Caesalpinia sappan L. The current study was aimed to explore the effect of PrA on atherosclerosis (AS). Materials and Methods: Firstly, the experimental model of AS was established in rabbits by two-month feeding of high fat diet. Then, the rabbits were randomly divided into five groups and treated with continuous high ...

Yanofsky (1) originally proposed N-(5’-phosphoribosyl)anthranilic acid as the first intermediate after anthranilic acid in tryptophan biosynthesis in microorganisms. Evidence was subsequently found which suggested that this compound is formed enzymatically from anthranilic acid and ribosylpyrophosphate 5-phosphate (2, 3). Although the dephosphorylated form of PRA,’ N-ribosylanthranilic acid, ha...

Importance Measures (IMs) are used to rank the risk contributing factors in Probabilistic Risk Assessment (PRA). In this paper, existing IM methodologies are analyzed in order to select the most suitable IM for an Integrated PRA (IPRA) of Nuclear Power Plants. In IPRA, the classical PRA of the plant is used, but specific areas of concern (e.g., fire, GSI-191, organizational factors, and seismic...

The aim of our study was to evaluate the physiological and pathological variations of plural renal arteries in individuals of various constitutional types. Data about sixty-six renal angiographies obtained post-mortem from 35 traffic accident victims were compared with 68 aortonephrograms of 35 randomly selected patients of the Medical Department. During the autopsy of the traffic casualties no...