QSP-10 APPLICATION OF AN IN SILICO PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL TO SIMULATE ORAL DRUG BIOAVAILABILITY OF ATORVASTATIN ACID AND CYCLOSPORINE POST BARIATRIC SURGERY. A. S. Darwich,1 D. Pade,2 K. Rowland-Yeo,2 M. Jamei,2 A. Åsberg,3 H. Christensen,3 D. M. Ashcroft,1 A. Rostami-Hodjegan1; 1Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, United Kingd...

 Given that improvement in efficiency is a major resource to economic development, this can be applied to each domestic sector of an economy. The objective of this paper is to measure technical efficiency of the Iranian Post Company across the country’s provinces using data envelopment analysis (DEA). The ranking of technical efficiency has been calculated by using collected data on post offi...

nce Abbie Leibowitz, MD knew he would be leaving his post as chief medical officer at Aetna, he began brainstorming new business ideas with former colleagues at weekly coffee meetings. The former medical director eventually became an entrepreneur, helping to launch a company that fills gaps in the health care system. Leibowitz’s company, Health Advocate links nurse advisors with individuals who...

Background: Executive compensation has become a controversial topic globally. Recent and past incidents of labour unrest, including those that plagued the South African mining sector in 2012, highlighted level controversy on subject. Purpose: The purpose this study was to investigate relationship between executive company performance Johannesburg Stock Exchange (JSE). Methodology: quantitative ...

Harvest and post-harvest operations constitute principal constraints to rice production, especially in irrigated systems, because of the larger yield that has to be handled. Post-harvest crop losses of up to 35% have been reported and attributed to inefficiency of manual threshing of rice by small-scale farmers. This leads to poor grain quality and rejection of locally produced rice. The Africa...

The problem of post-processing of a classified image is addressed from the point of view of the Dempster–Shafer theory of evidence. Each neighbour of a pixel being analyzed is considered as an item of evidence supporting particular hypotheses regarding the class label of that pixel. The strength of support is defined as a function of the degree of uncertainty in class label of the neighbour, an...

This paper empirically investigates the effect of policyholders’ private information about risky traffic behavior on automobile insurance coverage and ex post risk. It combines insurance company information with the policyholders’ private information on risky traffic behavior (traffic violations) that is not accessible to the insurance company. It is demonstrated that being unable to reject the...