A key event in nuclear formation is the assembly of functional nuclear pores. We have used a nuclear reconstitution system derived from Xenopus eggs to examine the process of nuclear pore assembly in vitro. With this system, we have identified three reagents which interfere with nuclear pore assembly, NEM, GTP gamma S, and the Ca++ chelator, BAPTA. These reagents have allowed us to determine th...

In the present study, Floating Drug Delivery Beads (FDDS) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. In order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the co...

Cementation factor is a critical parameter, which affects water saturation calculation. In carbonate rocks, due to the sensitivity of this parameter to pore type, water saturation estimation has associated with high inaccuracy. Hence developing a reliable mathematical strategy to determine these properties accurately is of crucial importance. To this end, genetic algorithm pattern search is emp...

Enhanced Geothermal Systems (EGS) are engineered reservoirs created to economically extract heat from low permeability and/or porosity geothermal resources. Existing geochemical reactive transport models for such systems lack essential data on the structure of the pore systems in geothermal reservoirs, and how they evolve in the relevant ranges of temperature, pressure, composition, and length ...

We present a model for pore stabilization in membranes without surface tension. Whereas an isolated pore is always unstable (since it either shrinks, tending to reseal, or grows without bound until membrane disintegration), it is shown that excluded volume interactions in a system of many pores can stabilize individual pores of a given size in a certain range of model parameters. For such a mul...

The phenylalanine-glycine-repeat nucleoporins (FG-Nups), which occupy the lumen of the nuclear pore complex (NPC), are critical for transport between the nucleus and cytosol. Although NPCs differ in composition across species, they are largely conserved in organization and function. Transport through the pore is on the millisecond timescale. Here, to explore the dynamics of nucleoporins on this...

In this study, shaking table tests are performed to investigate the behavior of excess pore water pressure in different soft soil-foundations of soil-structure interaction (SSI) system. The variation of the behaviors under cycled minor shock is observed. Moreover, The generation and variation mechanism of excess pore water pressure under earthquake excitation in different soft soilfoundations a...

Underground rocks usually have complex pore system with a variety of pore types and a wide range of pore size. The effects of pore structure on elastic wave attenuation cannot be neglected. We investigated the pore structure effects on P-wave scattering attenuation in dry rocks by pore-scale modeling based on the wave theory and the similarity principle. Our modeling results indicate that pore ...