نتایج جستجو برای: population in syn1 therefore

تعداد نتایج: 17038929  

2018
Sami P. Makaroun Katherine P. Himes

Objective  The retroviral genes encoding Syncytin-1 ( SYN1 ) and Syncytin-2 ( SYN2 ) are epigenetically regulated, uniquely expressed in the placenta and critical to placental function. We sought to determine if placental expression and methylation patterns of SYN1 and SYN2 from pregnancies complicated by fetal growth restriction (FGR) differed from physiologic small for gestational age (SGA) a...

Journal: :Journal of cell science 2003
Xue Cai Fugui Dong Richard E Edelmann Christopher A Makaroff

The faithful transmission of chromosomes during mitosis and meiosis requires the establishment and subsequent release of cohesion between replicated chromosomes. Sister chromatid cohesion is mediated, in large part, by the cohesin complex, which consists of four highly conserved proteins: SMC1, SMC3, SCC1/REC8 and SCC3. Mitotic cohesin complexes contain SSC1, whereas meiotic cohesin complexes c...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده زبانهای خارجی 1392

toury (1978:200) believes that translation is a kind of activity which inevitably involves at least two languages and two cultural traditions. being polite while asking for something takes place differently in different cultures and languages, therefore various strategies may be applied for making requests and also translation of them in order not to disturb or threaten the face or better to sa...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده ادبیات و علوم انسانی دکتر علی شریعتی 1392

a large number of single research studies on the effects of strategy-based instruction (sbi) in teaching english as a foreign or second language has been conducted so far. however, the lack of a comprehensive meta-analysis targeting the effectiveness of english language sbi is observed. moreover, the findings of experimental studies regarding the context of the english language, proficiency lev...

2013
Lily Paemka Vinit B. Mahajan Jessica M. Skeie Levi P. Sowers Salleh N. Ehaideb Pedro Gonzalez-Alegre Toshikuni Sasaoka Hirotaka Tao Asuka Miyagi Naoto Ueno Keizo Takao Tsuyoshi Miyakawa Shu Wu Benjamin W. Darbro Polly J. Ferguson Andrew A. Pieper Jeremiah K. Britt John A. Wemmie Danielle S. Rudd Thomas Wassink Hatem El-Shanti Heather C. Mefford Gemma L. Carvill J. Robert Manak Alexander G. Bassuk

The frequent comorbidity of Autism Spectrum Disorders (ASDs) with epilepsy suggests a shared underlying genetic susceptibility; several genes, when mutated, can contribute to both disorders. Recently, PRICKLE1 missense mutations were found to segregate with ASD. However, the mechanism by which mutations in this gene might contribute to ASD is unknown. To elucidate the role of PRICKLE1 in ASDs, ...

2013
Jun Sugimoto Makiko Sugimoto Helene Bernstein Yoshihiro Jinno Danny Schust

While common in viral infections and neoplasia, spontaneous cell-cell fusion, or syncytialization, is quite restricted in healthy tissues. Such fusion is essential to human placental development, where interactions between trophoblast-specific human endogenous retroviral (HERV) envelope proteins, called syncytins, and their widely-distributed cell surface receptors are centrally involved. We ha...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد 1388

abstract following innovations in the field of elt, a new topic which has recently attracted a lot of attention is metaphor analysis. although this area of research is still in its infancy in elt, it seems that the idea can shed more light on the puzzle of english language learning and teaching. therefore, the major aim of this study is to analyze language learning and teaching in formal a...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت معلم تهران - دانشکده علوم 1372

in this study reference as one of the five cohesive devices in the achievement of textuality in english and persian narrative/descripitive written texts is focused on and analysed . to do so , the theoretical framework elaborated by halliday and hasan (1976) and its version adapted by the writer to match the sub-types of reference in farsi are applied to the analysis of reference in english and...

2013
Maila Giannandrea Fabrizia C. Guarnieri Niels H. Gehring Elena Monzani Fabio Benfenati Andreas E. Kulozik Flavia Valtorta

Synapsins are a family of neuronal phosphoproteins associated with the cytosolic surface of synaptic vesicles. Experimental evidence suggests a role for synapsins in synaptic vesicle clustering and recycling at the presynaptic terminal, as well as in neuronal development and synaptogenesis. Synapsin knock-out (Syn1(-/-) ) mice display an epileptic phenotype and mutations in the SYN1 gene have b...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Yves Bourne Hartmuth C Kolb Zoran Radić K Barry Sharpless Palmer Taylor Pascale Marchot

The 1,3-dipolar cycloaddition reaction between unactivated azides and acetylenes proceeds exceedingly slowly at room temperature. However, considerable rate acceleration is observed when this reaction occurs inside the active center gorge of acetylcholinesterase (AChE) between certain azide and acetylene reactants, attached via methylene chains to specific inhibitor moieties selective for the a...

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