The objective of the study was to prepare mefenamic acid (MA) sustained release matrix pellets and investigate the formulation parameters affecting pellet attributes and drug release in vitro. Amixer torque rheometer (MTR) was used to characterize the rheological properties of wet mass used in pellet formulation. Mefenamic acid pellets were prepared by extrusion/spheronization techniques using ...

Now a day transdermal drug deliveries are increasing rapidly for the treatment of various diseases so the present study was conducted on different penetration enhancers for permeation of antidiabetic drug, glipizide (sulfonyl urea derivative) through skin. Different types of penetration enhancers such as terpenes and terpenoids, pyrrolidones, oxazolidinones, fatty acids etc are used for permeat...

The use of 5-aminolevulinic acid to induce endogenous porphyrins for the purpose of detection of epithelial cancers is being studied extensively in many centres around the world. The challenge is to prepare an efficacious formulation of 5-ALA for the purpose of cancer detection. In this study, we compared two formulations of topical 5-ALA applications with intravenous administration in NPC/CNE-...

Copper hollow fibers were prepared via dry-wet spinning of a polymer solution N-methylpyrrolidone, Polyetherimide, Polyvinyl Pyrolidone, and copper particles sizes in the range 1–2 µm. To remove template molecules to sinter particles, time calcination was varied 1–4 h at 600 °C. This temperature determined based on Thermal Gravimetric Analysis (TGA), showing completion hydrocarbon removal this ...

The present study was aimed to develop the Glimepiride (GLM) loaded nanosuspension by different methods for increasing solubility of GLM. Twelve formulations were prepared combination method (FG), which included antisolvent precipitation followed sonication (Method 1) selecting drug and polymer in ratio 1:10, 1:20 1:30. Further 6 nanoprecipitation (Fg) 2) using polymers like polyvinyl pyrolidon...

four separate experiments were conducted to study the effects of factors controlling the establishment of explants from two walnut genotypes z60 and z63 (damavand). factors were explant type, sampling time, explant orientation on the growth medium and antioxidants type. the explants were collected from the collection garden of tooyserkan walnuts research station. four explant types (apical meri...

This investigation evaluates the effectiveness of UV-365 nm/S2O8 2process in degrading polyvinyl alcohol in aqueous solutions. The effects of pH, Na2S2O8 dosage, and temperature on the degradation efficiency of polyvinyl alcohol were studied. Under acidic conditions, the degradation efficiency of polyvinyl alcohol exceeded that under alkaline conditions. Additionally, a higher Na2S2O8 dosage an...

polyvinyl butyral (pvb) was synthesized by condensation reaction of polyvinyl alcohol (pva) with butanal in aqueous medium containing an effective emulsifier and an inorganic acid as catalyst. the product was characterized by, ir, tg and dtg techniques. percentage of vinyl alcohol groups in the pvb was determined by a chemical method according to a standard method. some clear and soft film samp...

Vinyl acetate is a colorless, flammable liquid that also has a characteristic smell that can quickly become irritating. This monomer is used principally in the production of polyvinyl acetate (PVAc) and other vinyl acetate co-polymers. Polyvinyl acetate is a precursor of polyvinilyc alcohol and polyvinyl acetate resins (PVA). Vinyl acetate is also copolymerized as a minor raw material for vinyl...

The rheological response of blends obtained from quaternized polysulfone and polyvinyl alcohol in N-methyl-2pyrrolidone as against structural peculiarity of polymers from the blend, composition of polymer mixtures, as well as the types of interactions were investigated. Results show that the variation of polyvinyl alcohol composition in the studied system determines changes of the rheological p...