Purpose: To prepare and evaluate bioadhesive buccal films of diltiazem hydrochloride (a L-type calcium channel blocker) for overcoming the limitations of frequent dosing, low bioavailability and gastrointestinal discomfort of oral delivery. Methods: Buccal films were prepared by solvent casting technique using sodium carboxymethylcellulose, polyvinyl pyrrolidone K-30 and polyvinyl alcohol. The ...

Anthocyanin/polyvinyl alcohol/chitosan composite membrane was prepared by solution casting method using chitosan (CS) and polyvinyl alcohol (PVA) as matrix natural pigment anthocyanin filler. The structures of the films were characterized Uv-visible reflectance spectrum (UV-VIS), Fourier infrared spectroscopy (FT-IR) scanning electron microscopy (SEM). effects adding anthocyanins on physical pr...

Zinc oxide nanoparticles have been synthesized by chemical reaction method.  Polyvinyl alcohol (PVA) composite film filled with nanometric, monodispersed zinc oxide nano particles prepared by PVA solution and nanozinc oxide. Polymer blend with ZnO nanoparticle composite film has prepared by casting technique.  The property of nano composites depends greatly on the chemistry of polymer matrices....

Zinc oxide nanoparticles have been synthesized by chemical reaction method.  Polyvinyl alcohol (PVA) composite film filled with nanometric, monodispersed zinc oxide nano particles prepared by PVA solution and nanozinc oxide. Polymer blend with ZnO nanoparticle composite film has prepared by casting technique.  The property of nano composites depends greatly on the chemistry of polymer matrices....

1. Abstract: The objective of this work was to develop suitable film formulations of ketorolac tromethamine (KT) for transdermal use and to investigate the effect of film composition and permeation enhancers on the in-vitro release and skin permeation of the drug. Polyvinyl alcohol (PVA), sodium carboxymethylcellulose (NaCMC), and chitosan were used as film-forming polymers. The adhesive hydrop...

carboxymethyl cellulose (cmc)-polyvinyl alcohol (pvoh) blend film, containing 0-10% cellulose nanowhiskers (cnw), was produced through casting method, while physical properties of the films being investigated. cmc-pvoh-cnw nanocomposites, were prepared with a diluted suspension of cellulose nanowhiskers. nanowhiskers suspension was prepared through acid hydrolysis of cotton linter by sulfuric a...

Polymer film dosage forms of local anesthetics have been developed. Drug release from polymeric forms is investigated. Drug containing polymeric films shows a high initial release rate and the matrix-controlled release for more 6-8 h. The release data depends on drug loading and polymer structure. The possibility of application of polyvinyl alcohol for prolongation of anesthetics is show.

Octyl enamine-grafted acetoacetylated polyvinyl alcohol film (AAPVA x –OA) with a “soft-core–hard-sheath” layered structure was prepared through simple soaking. The shows excellent mechanical property and good programmable shape deformation.

Silk sericin (SS) is a glue-like protein from silkworm cocoon. With its outstanding moisturization and activation collagen synthesis properties, silk protein is applied for wound healing. Since wound dressing in film preparation can facilitate patients’ convenience and reduce risk of wound contraction, SS and polyvinyl alcohol (PVA) films were prepared with various concentrations of SS. Their p...

The oxygen transmission rate of a PET coated film showed 37-fold decrease using dispersion LDH nanosheets in polyvinyl alcohol that was prior aged for 8 weeks compared to the with equivalent freshly prepared LDH/PVA dispersion.