Colorectal cancer (CRC) is one of the most common forms of cancer worldwide and familial adenomatous polyposis (FAP) accounts for approximately 1% of all CRCs. Adenomatous polyposis syndromes can be divided into; familial adenomatous polyposis (FAP) - classic FAP and attenuated familial adenomatous polyposis (AFAP), MUTYH-associated polyposis (MAP), NTHL1-associated polyposis (NAP) and polymera...

COLORECTAL CANCER IS CLASSIFIED IN TO THREE FORMS sporadic (70-75%), familial (20-25%) and hereditary (5-10%). hereditary colorectal cancer syndromes classified into two different subtypes: polyposis and non polyposis. Familial Adenomatous polyposis (FAP; OMIM #175100) is the most common polyposis syndrome, account for <1% of colorectal cancer incidence and characterized by germline mutations i...

although several treatments have been suggested for nasal polyposis, from medical to surgical, there is no standard guideline for the management of this disease. during recent years increasing attention has been directed toward the effects of macrolide antibiotics on chronic sinusitis and nasal polyposis. in this study,  the efficacy of clarithromycin on severe nasal polyposis were examined. in...

introduction: to evaluate the most sensitive symptom to predict early recurrence of nasal polyposis. prospective longitudinal cohort study. tertiary university referral center with accredited otorhinolaryngology residency programs.  materials and methods: in this prospective study, we evaluated 62 patients with diffuse nasal polyposis. all patients underwent functional endoscopic sinus surgery....

Ethmoid polyposis are the nasal polyps which developed from ethmoidal sinuses located between nose and eyes. Usually it is allergic in nature can be multiple, grape like masses. The estimated ethmoid prevalence India 4%. In this case study, a 61 year old female patient was admitted with complaints of severe block since approximately 6 months.&#x0D; Keywords: polyposis, Nasal polyp, Antro-choana...

for many years, it was thought that nasal polyps are small tumors of the nasal or sinus mucosa. however, it is now believed that nasal polyps are formed as a result of frequent local swelling of nasal or sinus mucosa, which enlarge by increasing sub-mucosal edema and then expose to the air pipe and cause some symptoms. however, the main cause of polyp formation is not exactly understood. the pr...

Familial adenomatous polyposis is an archetypal disease illustrating the genetic basis of human cancer. The adenomatous polyposis coli gene functions as a tumor suppressor with hundreds of known mutations that result in a defective adenomatous polyposis coli protein. In addition to the certain fate of colon cancer without colectomy, patients with familial adenomatous polyposis are also at incre...

Mantle cell lymphoma is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. The gastrointestinal tract is the predominant site of extranodal involvement in the form of multiple lymphomatous polyposis. Multiple lymphomatous polyposis due to mantle cell lymphoma presenting with intussusception is ...