نتایج جستجو برای: polyomaviridae

تعداد نتایج: 75  

2013
Cillian F. De Gascun Michael J. Carr

JC and BK polyomaviruses were discovered over 40 years ago and have become increasingly prevalent causes of morbidity and mortality in a variety of distinct, immunocompromised patient cohorts. The recent discoveries of eight new members of the Polyomaviridae family that are capable of infecting humans suggest that there are more to be discovered and raise the possibility that they may play a mo...

2017
Mikk Puustusmaa Heleri Kirsip Kevin Gaston Aare Abroi

Almost a century has passed since the discovery of papillomaviruses. A few decades of research have given a wealth of information on the molecular biology of papillomaviruses. Several excellent studies have been performed looking at the long- and short-term evolution of these viruses. However, when and how papillomaviruses originate is still a mystery. In this study, we systematically searched ...

2017
Jinik Hwang So Yun Park Mirye Park Sukchan Lee Taek-Kyun Lee

Viruses are the most abundant biological entities in the oceans, and account for a significant amount of the genetic diversity of marine ecosystems. However, there is little detailed information about the biodiversity of viruses in marine environments. Rapid advances in metagenomics have enabled the identification of previously unknown marine viruses. We performed metagenomic profiling of seawa...

2016
Sarat Kuppachi Deepkamal Kaur Danniele G. Holanda Christie P. Thomas

BK virus (BKV) is a non-enveloped DNA virus of the polyomaviridae family that causes an interstitial nephritis in immunosuppressed patients. BKV nephropathy is now a leading cause of chronic kidney disease and early allograft failure following kidney transplantation. It is also known to cause renal disease with a progressive decline in kidney function in non-renal solid organ transplant (NRSOT)...

Journal: :Journal of virology 2016
Nadège F Madinda Bernhard Ehlers Joel O Wertheim Chantal Akoua-Koffi Richard A Bergl Christophe Boesch Dieudonné Boji Mungu Akonkwa Winnie Eckardt Barbara Fruth Thomas R Gillespie Maryke Gray Gottfried Hohmann Stomy Karhemere Deo Kujirakwinja Kevin Langergraber Jean-Jacques Muyembe Radar Nishuli Maude Pauly Klara J Petrzelkova Martha M Robbins Angelique Todd Grit Schubert Tara S Stoinski Roman M Wittig Klaus Zuberbühler Martine Peeters Fabian H Leendertz Sébastien Calvignac-Spencer

UNLABELLED It has long been hypothesized that polyomaviruses (PyV; family Polyomaviridae) codiverged with their animal hosts. In contrast, recent analyses suggested that codivergence may only marginally influence the evolution of PyV. We reassess this question by focusing on a single lineage of PyV infecting hominine hosts, the Merkel cell polyomavirus (MCPyV) lineage. By characterizing the gen...

2012
Serena Delbue Manola Comar Pasquale Ferrante

The polyomaviruses are small DNA viruses that can establish latency in the human host. The name polyomavirus is derived from the Greek roots poly-, which means "many," and -oma, which means "tumours." These viruses were originally isolated in mouse (mPyV) and in monkey (SV40). In 1971, the first human polyomaviruses BK and JC were isolated and subsequently demonstrated to be ubiquitous in the h...

2015
Piyada Linsuwanon Yong Poovorawan Linlin Li Xutao Deng Sompong Vongpunsawad Eric Delwart Charles Y. Chiu

Hand, foot, and mouth disease (HFMD) affects infant and young children. A viral metagenomic approach was used to identify the eukaryotic viruses in fecal samples from 29 Thai children with clinical diagnosis of HFMD collected during the 2012 outbreak. These children had previously tested negative by PCR for enterovirus 71 and coxsackievirus A16 and A6. Deep sequencing revealed nine virus famili...

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