objective(s): the aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. materials and methods:matrix-mini-tablets of lornoxicam were prepared by direct compression method using microsomal enzyme dependent and ph-sensitive polymers which were further filled into an empty hpmc capsule. to asses...

in this work application of seven synthetic polymers as adsorbents for the removal of hg(ii) from aqueous solution was studied. the equilibrium studies are systematically carried out in a batch process, covering various process parameters that include agitation time, adsorbent dosage, and ph of the aqueous solution. variations of hg(ii) concentration in solution have been studied through measur...

patient noncompliance to current tuberculosis (tb) therapy owing to multidrug administration daily leads to treatment failure and emergence of multidrug resistant and extensively drug resistant tb. to avoid the daily dosing, application of nanotechnology is the only viable solution by virtue of sustained release of drugs. other potential advantages of the system include the possibility of selec...

an analytical equation of state (eos) developed by ihm-song-mason (ism) has been applied tocalculate some thermophysical properties of molten polymers including poly (1-octene) (po), poly (vinylmethyl ether) (pvme), poly (vinyl chloride) (pvc), and poly (styrene) (ps). three temperature-dependentparameters of the ism eos have been determined based on the alternative scaling constants, dispersiv...

objective polyethylenimine (pei), a readily available synthetic polycation which has high transfection efficiency owing to its buffering capacity was introduced for transfection a few years ago. but it has been reported that pei is cytotoxic in many cell lines. in this study, in order to enhance the transfection efficiency of 10 kda pei and reduce its toxicity, hydrophobic residues were grafted...

in this paper, electronic, structural, and spectroscopic properties of mono-, di-, tri-, andtetrafluorothiophenes and their radical cations are studied using the density functional theory andb3lyp method with 6-311++g** basis set. also the effects of the number and position of thesubstituent on the electrochemical properties of the thiophene ring have been studied usingoptimized structures obta...

Nanoparticles made of biodegradable polymers has become the best approach for nanoparticle making due to their compatibility with the human body. New glycerol adipate polymers with hydroxyl group substituted with different percent of acyl group, sited as figures within the abbreviated name in the text, and triptophan were synthesized and proposed to be used in the preparction of dexamethason ph...

microbial cells are producers of natural polymers present in plant cells. production of pullulan (an extracellular microbial polysaccharide) by aureobasidium pullularia pullulans (p. pullulans) was studied under fermentation conditions, and kinetic parameters were determined. pullulan formation obeyed a growth and non-growth associated term. phb (polyhydroxybutyrates) an intracellular biopolyme...