Recently, there is growing interest in finding naturally occurring antioxidants for use in foods or medicinal materials to replace synthetic antioxidants, which are being restricted due to their carcinogenicity [1]. Antioxidants are secondary constituents or metabolites found naturally in plants. They are mainly phenolics serving in plant defense mechanisms to counteract reactive oxygen species...

Dormancy and germination requirements were investigated in seeds of Ferula gummosa Boiss (Apiaceae) and Teucrium polium L. (Labiatae). Seeds of both species were subjected to different treatments including various levels of GA3, HNO3, H2SO4, chilling and soaking with water at different temperatures. Germination of both species increased at higher concentrations of GA3. In the case of F. gummosa...

OBJECTIVES Wound healing represents a dynamic physiological process influenced by many factors. The aim of the present study was to evaluate the effects of Teucrium polium honey on the wound healing and tensile strength in rat. MATERIALS AND METHODS Thirty-six Sprague-Dawley rats were randomly divided into four equal (n= 9) treatment and control groups. Two full-thickness wounds were made ove...

BACKGROUND Teucrium polium is an analgesic, antidiabetic and antilipeidemic herbal medicament. The aim of this survey was to evaluate the effect of aqueous extract T. polium on liver enzymes linked to liver dysfunction, serum lipids and glucose, in diabetic male rats. METHODS A total of 20 Sprague-Dawly male rats became diabetic by intraperitoneal injection of streptozotocin (60 mg/kg). the a...

BACKGROUND Diabetes has an adverse effect on spermatogenesis by rising oxidative stress. OBJECTIVE The aim of this study was to investigate the effect of Teucrium Polium extract administration on spermatogenesis and testicular structure in diabetic rats induced with Streptozotocin. MATERIALS AND METHODS 32 male Wistar rats were randomly divided into four groups (n=8/each): control group, di...

Тhe aim of the study was identification and determination of the content of flavonoids in dry extracts of Teucrium polium, collected from Republic of Macedonia. Two different drying procedures were used, freeze and spray draying. In freeze-dried (FDE) and spray-dried (SDE) extracts of aerial parts of T. polium five flavone aglycones (luteolin, apigenin, cirsiliol, cirsimaritin and cirsilineol) ...

Antibiotics provide the main basis for the therapy of microbial (bacterial and fungal) infections. Since the discovery of these antibiotics and their use as chemotherapeutic agents there was a belief in the medical fraternity that this would lead to the eventual eradication of infectious diseases. However, overuse of antibiotics has become the major factor in the emergence and dissemination of ...

Introduction Reactive oxygen species (ROS) have been shown to play a critical role in many diseases such as diabetes mellitus, cancer, Alzheimer, arteriosclerosis and other conditions. Chronic glucose levels in blood or cells of diabetic patients are known to cause oxidative damages, followed by an increasing in ROS production and/or dysfunction of antioxidant defense system (enzyme or non-enzy...

The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment wi...

In an effort to evaluate the hypoglycemic activity of T. polium, the crude extract was administered orally to a group of Streptozotocin induced diabetic rats for 6 consecutive weeks. Significant decrease in blood glucose by 64%, total bilirubin by 35%, glutamate oxaloacetate transferase by 48% and glutamate pyruvate transferase by 30% was observed compared to untreated diabetic rats. However, t...