نتایج جستجو برای: poikiloderma with neutropenia syndrome

تعداد نتایج: 9376087  

2012
Luciana Mendes Lisiane Nogueira Virginia Vilasboas Carolina Talhari Sinésio Talhari Mônica Santos Nilton Lins

Kindler syndrome is a rare autosomal recessive genodermatosis characterized by trauma-induced blisters, progressive poikiloderma and varying degrees of photosensitivity. In 2003, loss-of-function mutations were identified in the gene KIND1 mapped to chromosome 20p12.3. In this paper, we report Kindler syndrome in two children born to consanguineous parents presenting acral blistering, photosens...

2017
Raphaëlle Goussot Megana Prasad Corinne Stoetzel Cédric Lenormand Hélène Dollfus Dan Lipsker

IPMN: intraductal papillary mucinous neoplasm POIKTMP: hereditary fibrosing poikiloderma with tendon contractures, myopathy, and pulmonary fibrosis RTS: Rothmund-Thomson syndrome H ereditary fibrosing poikiloderma with tendon contractures, myopathy, and pulmonary fibrosis (POIKTMP [MIM#615704]) is an extremely rare syndromic form of autosomal dominant poikiloderma. This genetic disorder was fir...

صیرفی, حسن , غنی نژاد, هایده , فرنقی, فرشاد ,

Kindler syndrome is characterized by acral blister formation in infancy and childhood, poikiloderma and cutaneous atrophy. Undoubtedly, similarities of the clinical features exist between Kindler syndrome and Epidermolysis bullosa simplex with mottled pigmentation. In this article, we report 3 patients with Kindler syndrome. Until the Bullous component of Kindler syndrome is more completely und...

2016
Aude‐Annick Suter Peter Itin Karl Heinimann Munaza Ahmed Tazeen Ashraf Helen Fryssira Usha Kini Pablo Lapunzina Peter Miny Mette Sommerlund Mohnish Suri Signe Vaeth Pradeep Vasudevan Sabina Gallati

BACKGROUND Poikiloderma is defined as a chronic skin condition presenting with a combination of punctate atrophy, areas of depigmentation, hyperpigmentation and telangiectasia. In a variety of hereditary syndromes such as Rothmund-Thomson syndrome (RTS), Clericuzio-type poikiloderma with neutropenia (PN) and Dyskeratosis Congenita (DC), poikiloderma occurs as one of the main symptoms. Here, we ...

2013
Andrzej Dziembowski Pekka Lappalainen

Ribonucleases are central components of the eukaryotic RNA processing and decay machineries. They participate in processing of stable RNA species and pre-mRNA molecules as well as remove unwanted molecules like: RNA processing by-products and malformed RNA species that are identified by surveillance pathways. Finally, ribonucleases participle in mRNA turnover and regulated mRNA decay pathways. ...

Journal: :acta medica iranica 0
h. ghaninejad k. balighi a. ehsani m. hoseini

kindler's syndrome is a rare entity of unknown cause characterized by acral blisters early in life followed by progressive diffuse poikiloderma and cutaneous atrophy. the inheritance pattern of this syndrome is not clear. we report four iranian siblings (three boys and one girl) with this syndrome, who were the result of a consanguineous marriage. in addition to the usual manifestations of the ...

Journal: :Gaceta medica de Mexico 2016
Gloria María Rosales-Solis César Adrián Martínez-Longoria Guillermo Antonio Guerrero-González Jorge Ocampo-Garza Jorge Ocampo-Candiani

Bloom syndrome is an extremely rare inherited disorder. We present a case of Bloom syndrome with a chromosomal study in a Mexican five-year-old patient who presented growth retardation, narrow facies with poikiloderma, café-au-lait, macules and photosensitivity.

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