The Drosophila Pan Gu (PNG) kinase complex regulates hundreds of maternal mRNAs that become translationally repressed or activated as the oocyte transitions to an embryo. In a previous paper (Hara et al., 2017), we demonstrated PNG activity is under tight developmental control and restricted to this transition. Here, examination of PNG specificity showed it to be a Thr-kinase yet lacking a clea...

Macrophages (MAC) and polymorphonuclear granulocytes (PNG) are professional phagocytes which perform essential functions in antibacterial defense. The intracellular bacterium Mycobacterium tuberculosis persists and replicates in resting macrophages. Although it is generally assumed that activated MAC are central to protection against M. tuberculosis, PNG may also contribute to defense. We wonde...

The early cell cycles of Drosophila embryogenesis involve rapid oscillations between S phase and mitosis. These unique S-M cycles are driven by maternal stockpiles of components necessary for DNA replication and mitosis. Three genes, pan gu (png), plutonium (plu), and giant nuclei (gnu) are required to control the cell cycle specifically at the onset of Drosophila development by inhibiting DNA ...

Dengue is the most common cause of mosquito-borne viral disease in humans, and is endemic in more than 100 tropical and subtropical countries. Periodic outbreaks of dengue have been reported in Papua New Guinea (PNG), but there is only limited knowledge of its endemicity and disease burden. To help elucidate the status of the dengue viruses (DENVs) in PNG, we performed envelope (E) gene sequenc...

OBJECTIVE To examine the correlation between HIV prevalence and male circumcision and other foreskin cutting practices across the four regions of Papua New Guinea (PNG). DESIGN An ecological substudy using unique data from an interdisciplinary research programme to evaluate the acceptability, sociocultural context and public health impact of male circumcision for HIV prevention in PNG. METH...

This figure "fig2-1.png" is available in "png"" format from: This figure "fig3-1.png" is available in "png"" format from: This figure "fig4-1.png" is available in "png"" format from: This figure "fig5-1.png" is available in "png"" format from: This figure "fig6-1.png" is available in "png"" format from: { 15 { FIGURE CAPTIONS Fig. 1.| The PDF of the density eld from the 1.2 Jy IRAS galaxy catal...

We determined the power and its graph simulations on discrete Poisson Chi-square distributions. There are four important steps of research methodology summarized as follow: (1) determine sufficient statistics (if possible), (2) create rejection area (UMPT test is sometime used), (3) derive formula power, (4) graphs using data (in simulation). The their curves then created <img src=image/1342768...