background platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. the primary objective of this study was to use autologous platelet rich plasma (prp) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. methods in a single cen...

background cartilage tissue has limited regenerative capacity and the management of cartilage defects has always been a challenging issue. platelet-rich plasma (prp) has been recently been used to improve healing of cartilage defects. in the present experiment, we aimed to investigate the effects of prp on regeneration capacity as well as survival of the cartilage grafts in a rabbit model. meth...

background autologous platelet concentrate has been used to improve the function and regeneration of injured tissues. tendinopathies are common in clinical practice, although long-term treatment is required. on the basis of lead time, we compared the effect of using platelet-rich plasma (prp) and platelet-rich fibrin (prf) in repairing rat achilles tendon. methods the effectiveness of using prp...

background: the purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (prp) and platelet-rich fibrin (prf) containing stromal cell-derived factor-1 (sdf1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect. methods: we created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen mat...

patients and methods seventy patients with chronic partial supraspinatus tears in magnetic resonance imaging were randomized into two groups; prp (n = 35) and pt (n = 35). before the treatment, at the end of the treatment and at the 12th month after the end of the treatment, range of motion (rom), visual analog scale (vas) for pain, disabilities of arm, shoulder and hand questionnaire (dash), n...

background: plantar fasciitis (pf) is a common foot complaint, affects both active sportsmen and physically inactive middle age group. it is believed that pf results from degenerative changes rather than inflammation. platelet?rich plasma (prp) therapy has been introduced as an alternative therapy for pf. this study is aimed to systematically review to the effectiveness and relevant factors of ...

the clinical use of prp therapy in the practical setting of orthopaedic fields is increasing partly because of the accessibility of devices that are used in outpatient preparation and delivery. another reason is the strong advertisement of prp procedures as the ultimate treatment and novel technology for knee problems by a few orthopaedic surgeons based on claims of abundant scientific evidence...

background: osteoarthritis is a disabling musculoskeletal disease with no definite treatment. this study compared the effect of platelet-rich plasma (prp) and transcutaneous electrical nerve stimulation (tens) plus exercise in the treatment of patients with knee joint osteoarthritis.   methods : 54 eligible patients with knee osteoarthritis were randomly allocated into two groups. (irct20121106...

background facial wrinkles develop over the natural aging process. the demand to treat these wrinkles is increasing. several treatment options are available. objectives we aimed to investigate the effect of fat injection and its combination with platelet-rich plasma (prp) on facial wrinkles. patients and methods we recruited 28 patients who were candidates for the treatment of facial wrinkles i...

objectives effect of using autologous platelet-rich plasma (prp) on pain reduction in patients with pilonidal abscess, subjected to extensive surgical removal tissue, was investigated through a clinical trial. patients and methods the trial was conducted on two groups from the center for surgical research at mashhad university of medical sciences located at ghaem hospital in mashhad city in 201...