Pectates lyase (Pel) plays an important role in bacteria pathogenicity. The crystal structure of Pel from Acidovorax citrulli (AcPel) has been solved to 1.37 Å resolution. AcPel belongs to the polysaccharide lyase family 1 (PL1), which has a characteristic right-handed β-helix fold. AcPel is similar with other Pels in the PL1 family, but also shows some differences at the substrate binding site.

We investigated the role of homeobox-containing genes in human hematopoiesis because homeobox genes (i) control cell fate in the Drosophila embryo, (ii) are expressed in specific patterns in human embryos, and (iii) appear to function as transcription factors that control cell phenotype in other mammalian organs. Using four homeobox probes from the HOX2 locus and a previously undescribed homeob...

Abstract The Improving Connectivity in the Central Forest Spine (IC-CFS) is funded by Malaysian Government (GOM) and Global Environment Facility (GEF). IC-CFS main objective to re-establish, maintain, improve connectivity within corridors create linkages between fragmented forests. carbon stock assessment component required evaluate corridors. study was conducted at Primary Linkages Pahang (C-P...

Penyerpihan habitat adalah pemacu kepada isu kepupusan pelbagai spesies yang menyebabkan serpihan hutan menjadi lebih kecil dan terpencil. Kajian ini dijalankan bertujuan untuk mengukur komposisi serta kepelbagaian mamalia terestrial (bersaiz sederhana besar) di koridor ekologi CFS1:PL1 CFS1:PL6. Pemasangan 211 perangkap kamera kedua-dua berjaya menghasilkan sejumlah 43,799 imej bebas (8,594 pe...

Both P-selectin glycoprotein ligand-1 (PSGL-1) and L-selectin are localized on the microvilli of neutrophils and have been implicated in the attachment of neutrophils to P-selectin or E-selectin. We directly compared the attachment and rolling of neutrophils on P-selectin and E-selectin under flow, with emphasis on the functions of PSGL-1 and L-selectin. Flowing neutrophils attached more avidly...

This study was designed to determine the effects of five different salinity levels (25, 30, 35, 40 and 45 ppt) on survival rate Farfantepenaeus aztecus larvae from Nauplius5 post-larvae1 (N5-PL1). For this purpose, 50 that reached N5 stage were stocked in 2-L round bottom glass flasks replications grown up PL1 at 27.6±0.4°C. At end study, as highest (44.00±23.15) protozoal stages obtained 35 pp...

Leukocyte rolling, an early and important step in the inflammatory response, is mediated by the selectin family of adhesion molecules. The selectins bind with low affinity to sialylated and fucosylated glycans such as sialyl Lewisx (sLex), but bind with high affinity to only a few specific glycoproteins on cell surfaces. One such glycoprotein is P-selectin glycoprotein ligand-1 (PSGL-1). The re...

Abst rac t We present two concept languages,, called PL1 and PL2 which are extensions of TC. We prove that the subsumption problem in these languages can be solved in polynomial time. Both languages include a construct for expressing inverse roles, which has not been considered up to now in tractable languages. In addition, PL1 includes number restrictions and negation of primitive concepts, wh...

OBJECTIVES Although the prognostic implications of visceral pleural invasion (VPI) are well established, it remains controversial whether the extent of VPI affects survival in patients with completely resected non-small-cell lung cancer (NSCLC). In addition, the impact of VPI according to nodal status is unclear. We evaluated the influence of the extent of pleural invasion on survival by analys...