several plant extracts and phytoconstituents, despite having excellent bioactivity in vitro, demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or destruction in gut. drug delivery system for polyphenolic phytoconstituents (phytosomes) was prepared by complexing polyphenolic phytoconstituents with phospholipid mainly phosphatidylcholine which bi...

Abstract: Background: Phytosome is a novel technique introduced by Indena that combines standardised herbal extract and phospholipid in preferably equal ratio to provide better absorption enhancing bioavailability. Purpose: The objective of proposed study prepare, optimise characterize phytosomes Murraya koenigii (Linn.) Spreng improve its antidiabetic properties. Materials Methods: Antisolvent...

Nuclear factor erythroid 2-related factor 2 (Nrf2) has been recognized as a transcription factor that controls mechanisms of cellular defense response by regulation of three classes of genes, including endogenous antioxidants, phase II detoxifying enzymes and transporters. Previous studies have revealed roles of Nrf2 in resistance to chemotherapeutic agents and high level expression of Nrf2 has...

Herbal medications have a diverse range of active constituents allowing us to use them in variety ways, but are poorly absorbed due their strong polarity and low lipophilicity, resulting bioavailability. The aim this research was improve bioavailability by development in-vitro evaluation phytosomes containing herbal extract Centella asiatica for its antioxidant gastroprotective activity. Phytos...

Introduction: Lucid morinda (L) A medium-sized evergreen tree of the Morinda genus, Benth (M. lucida, Rubiaceae) is a tropical West African rainforest plant that also known as Brimstone tree. In several nations, it utilized in traditional medicine to cure variety human ailments. Phytosomes are freshly developed herbal formulations have superior bioavailability and effects than phyto molecules o...