Introduction: Penumbra is an important property of the radiation beam to obtain a suitable margin surrounding the target volume. Therefore, the precise penumbra width determination in stereotactic radiotherapy is necessary for treatment planning. This study aimed to compare the obtained results of penumbra width by in-house and standard circul...

one of the signifiant risk factor of ischemic stroke is carotid artery occlusion. although surgical treatment was disappointing in these patient but there is a growing reports of sucessful endovascular treatment recently. in this technical note 56 year-old man who suffered from bilateral carotid occlusion was revascularized. the penumbra thrombosuction system was applied to reduce the risk of d...

In a search for new genes involved in the regulation of erythropoiesis, we identified murine Penumbra cDNA from a multipotent hematopoietic cell line based on its predominant expression in erythroblasts. Subsequently, we identified the human PENUMBRA from a bone marrow cDNA library. Penumbra is a new member of the tetraspanin superfamily of membrane proteins, many of which are thought to functi...

Context. The physical conditions leading the sunspot penumbra decay are poorly understood so far. Aims. We investigate photospheric magnetic and velocity properties of a during phase to advance current knowledge this process. Methods. A penumbral was observed with CRISP instrument at Swedish 1 m Solar Telescope on 2016 September 4 5 in active region NOAA 12585. During these days, full-Stokes sp...

BACKGROUND Penumbra characteristics play a significant role in dose delivery accuracy for radiation therapy. For treatment planning, penumbra width and radiation field offset strongly influence target dose conformity and organ at risk sparing. METHODS In this study, we present an analytical and numerical approach for evaluation of the rounded leaf end effect on penumbra characteristics. Based...

BACKGROUND The ability to quickly and efficiently identify the ischemic penumbra in the acute stroke clinical setting is an important goal for stroke researchers and clinicians. Early and accurate identification of potentially salvageable versus irreversibly infarcted brain tissue may enable selection of the most appropriate candidates for early stroke therapies and identify patients who may st...

Reactive gliosis is a process triggered in astrocytes after traumatic injury, yet the exact consequences of gliosis on cellular survival and neural regenerative processes in the injured brain remain only partly understood. One recently discovered feature influencing neuronal growth and differentiation is the physical stiffness of the environment surrounding pioneering neurites. In this study, t...

Peripheral stimulation and physical therapy can promote neurovascular plasticity and functional recovery after CNS disorders such as ischemic stroke. Using a rodent model of whisker-barrel cortex stroke, we have previously demonstrated that whisker activity promotes angiogenesis in the penumbra of the ischemic barrel cortex. This study explored the potential of increased peripheral activity to ...

BACKGROUND AND PURPOSE Prediction of the regions of the ischemic penumbra that are likely to progress to infarction is of great clinical interest. Whether lowered apparent diffusion coefficient (ADC) values were present in the ischemic penumbra of patients presenting with acute ischemic stroke and were specific to regions of the penumbra that proceeded to infarction was investigated. METHODS ...

Shadows serve as e ective cues for a user to recognize spatial relations among objects in 3D space. However simple shadows typically used in 3D interfaces are often insu cient for the purpose, and rendering of shadows with real penumbra are not only too costly for interactive interfaces, but also do not enhance their capabilities as spatial cues. Our proposal, layered penumbra is a new interact...