we used various screening techniques, clustering, decision tree and generalized rule induction (association) (gri) models and molecular phylogenic relationship to search for patterns of halophi-licy and to find features contribute to halolysin salt stability. we found met was the sole n-terminal amino acid in halolysin proteins, whereas other amino acids found at this position of oth-er proteas...

Motivation: Multiple coronavirus genomes are normally organized by genomic information in a phylogenic tree to illustrate evolutionary variations. A novel scheme is represented arrange various two indexes as 2D maps. Results: For genome, unique invariants of provide an absolute position on region real measurements. Clustering effects provided complementary from Phylogeny technology. Samples sev...

Emerging evidences suggest the heterogeneity of cancers limits the efficacy of immunotherapy. To search for optimal therapeutic targets, we used whole-exome sequencing data from 23 early cervical tumors from Chinese women to investigate the hierarchical structure of the somatic mutations and the predicted neo-epitopes based on their strong binding with major histocompatibility complex class I m...

Aquaporins are ubiquitous proteins that belong to the major intrinsic protein family. Previous studies have indicated that aquaporins are involved in multiple physiological processes in parasites, such as nutrient absorption and end product efflux, and thus, would be promising pharmacological agents in the fight against parasite infection. In the present paper, the authors analyzed the evolutio...

The evolution of ribosomal proteins of about 70 bacterial strains belonging to the family Enterobacteriaceae has been studied by use of previously reported data (S. Osawa, T. Itoh, and E. Otaka, J. Bacteriol. 107:168-178, 1971) and those obtained in this paper. The proximity of the bacteria was quantified by co-chromatographing the differentially labeled ribosomal proteins from two strains on a...

We develop a conceptual framework for valuing biodiversity from an economic perspective. We argue for a dynamic economic welfare measure of biodiversity that complements the literature on beneŽ t-cost approaches and genetic distance/phylogenic tree approaches. Using a uniŽ ed model of optimal economic management of an ecosystem under ecological and genetic constraints, we identify gains from ma...

A bacteria library was constructed from the caecum of a rabbit maintained under standard conditions. The complete gene 16S rRNA gene was sequenced. The 228 clones obtained were distributed in 70 operational taxonomic units (OTUs). The large majority of the OTUs were composed of one or two clones and seven OTUs contained half of the sequences. Fourteen sequences had high similarity to the sequen...

One of the most important measures for detecting molecular adaptations between species/lineages at the gene level is the comparison of relative fixation rates of synonymous (dS) and non-synonymous (dN) mutations. This study shows that the branch model is sensitive to tree topology and proposes an alternative approach, devogs, which does not require phylogenetic topology for analysis. We compare...

One of the most important species of the Bartonella genus is B. henselae that causes a zoonotic infection, cat scratch disease (CSD). The main source of the bacteria is cat and the carrier is Ctenocephalides felis flea. One hundred and forty nail and saliva samples were collected from 70 domestic cats. Positive samples for B. henselae were characterized by po...