The genus Phyllanthus (Phyllanthaceae) is distributed in tropical and subtropical regions, and its members are widely used as medicinal plants in many countries. We analyzed the nucleotide sequences of the internal transcribed spacers of ribosomal DNA of 56 plant samples covering 23 Phyllanthus species collected from various habitats in Thailand. Based on the sequence alignment, we constructed ...

Impact of Phyllanthus amarus extract on antioxidant enzymes in Drosophila melanogaster N. Manasa, J. S. Ashadevi

Phyllanthus amarus is an indigenous medicinal plant, with a folk reputation as hypoglycemic agent in Central and Southern India. In the present investigation hypoglycemic activity of ethanolic leaf extract of Phyllanthus amarus was evaluated using alloxan induced hyperglycemic mice. Blood glucose levels of all the mice of each group were tested before the treatments on fasting mice and then tes...

Objective: To assess the hepatoprotective effect of ethanolic extract of leaves and stem of Phyllanthus amarus and ethanolic extract of leaves of Tylophora indica against Isoniazid induced liver toxicity in experimental animals. Methods: Liver toxicity was induced by administering Isoniazid 27mg/kg orally for 30 days in Wistar albino rats. Ethanolic (90%) extracts of Phyllanthus amarus (PAEE) a...

Liver disease has become a global concern worldwide. In absence of reliable liver protective drugs in modem medicine, a large number of medicinal preparations are recommended for the treatment of liver disorders as they are believed to be harmless based on their natural origin. The aim of the present study was to determine the hepatoprotective activity of Phyllanthus amarus plant extract agains...

The aqueous extract of Phyllanthus amarus Schum & Thorn, was selected for preliminary phytochemical and antibacterial activity against human pathogens. Minimum inhibitory concentration was performed by broth dilution method and the zone of inhibition was studied by agar disc diffusion method at concentrations of 10 and 20 mg/ml in DMSO (Dimethyl Sulfoxide). The results revealed the antimicrobia...

The herbal preparations of Phyllathus amarus has been used extensively in indigenous system of medicine for treating many infectious diseases. A great deal of interest has been generated on the protective effects of whole plant extracts of Phyllanthus against mutagens. The present study was designed to evaluate the modifying effect of Phyllanthus extract against X –ray induced chromosomal damag...

Our research studies data suggest that, there were significant variations in the observed biochemical parameters. The level of TBARS in ethanol intoxicated rats increased two fold when compared with the control animals. The levels of GSH, SOD and CAT decreased significantly in the ethanol intoxicated rats. The level of GPx was increased in the ethanol intoxicated rats. The value of vitamin E in...

Phyllanthus amarus Schum. Thonn. is an indigenous medicinal plant, which has a folk reputation in central and southern India as hypoglycemic agent. The present investigation was carried out to evaluate the antidiabetic effect of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice. Blood glucose levels and body weights of control and diabetic mice were monitored. In the...