Norrie's disease, a congenital progressive oculo-acoustico-cerebral degenerative condition, is a sex linked recessive disorder. Previously described as atrophia oculi congeneti, it is associated with bilateral pseudotumour of the retina, lens, and corneal opacities, and phthisis bulbi. Some patients develop progressive deterioration of mental function and hearing. We report a Sri Lankan family ...

Experimental endogenous endophthalmitis was produced in infant rats by either intranasal or intraperitoneal inoculation with Haemophilus influenzae type b and 5 days of age. The ocular disease occurred in about 50% of bacteremic animals who survived to age 12 days and probably represents metastatic bacterial infection secondary to hematogenous seeding. The lesion was a highly destructive suppur...

Endophthalmitis is an intraocular inflammation involving both posterior and anterior segments, caused by bacterial or fungal infections. Here, we present a case series of five cases presented to the National Referral Hospital from January December 2017. Five eyes were identified, including exogenous endogenous odontogenic causes. All managed with vitrectomy, intravitreal antibiotics, systemic a...

PURPOSE To describe immunohistopathological findings in autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV). METHODS An enucleated eye specimen from a patient with Stage V ADNIV was examined using standard histopathological methods and lymphocyte markers. RESULTS A c.731T>C CAPN5 mutation resulted in a p.Leu244Pro substitution in calpain-5. The eye showed exudative retinal...

PURPOSE Evisceration is an alternative treatment modality to enucleation for many end-stage eye diseases. No study has addressed the indications for evisceration of eyes in Saudi Arabia. The aim of this study was to determine the current clinical indications for evisceration in patients at a tertiary eye care center and attempt clinicopathological correlation. METHODS Clinical records of pati...

CASE REPORT A 5-year-old male presented with bilateral poor vision, esotropia and a previous diagnosis of cataract since he was 1 year old. The physical examination revealed bilateral posterior paracentric capsule opacification, vitreous cavity with a permeable pulsatile blood filled hyaloid artery in both eyes. He was kept under observation. DISCUSSION Persistent hyaloid artery is an uncommo...

P hthisis bulbi implies, in clinical terminology, a shrunken globe, usually from ceased aqueous humor formation (phthisis meaning “wasting away”). The intraocular pressure approaches 0 mm Hg. As a consequence, the cornea becomes distorted and can develop edema and scarring, and the lens develops cataracts. Both seem to occur due to the lack of nutrition by the aqueous. In addition, edema can de...

To cite: Holla A, Gonsalves SRJ. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200793 DESCRIPTION A 70-year-old woman presented with a painless fleshy mass in the right eye of 3 months duration with no history of trauma. She gave a history of cataract surgery in the same eye 4 years ago. Examination revealed an irregular, black, fleshy, lobulated mass with v...