Volume 88, Number 7 www.aafp.org/afp American Family Physician 457 A 41-year-old man presented with a painful, erythematous, erosive, and scaly rash. It was symmetrically distributed over sun-exposed areas, involving his face, neck, dorsum of his hands and feet, and upper back (Figures 1 and 2). The rash and frequent loose stools had been present for several months. Neuropsychiatric evaluation ...

Bullous systemic lupus erythematosus is one of the rare autoantibody mediated skin manifestation of systemic lupus erythematosus (SLE) demonstrating subepidermal blistering with neutrophilic infiltrate histologically. We present a case of a 40-year-old Hispanic female who presented with a several months' history of multiple blistering pruritic skin lesions involving the face and trunk, a photos...

prolonged local consumption of anethum graveolens leaves, as an antihyperlipimic and antihypercholesterolemic agent, has been associated in some patients with skin disorders such as darkening and pigmentation mainly in the exposed areas such as face and hands.anethum graveolens belongs to the umbelliferae family which is belived to be rich in photoactive furocoumarins. an oraganic extract of th...

sand fly fever (sf) is an arthropod-borne viral disease, also known as “phlebotomus fever”, ‘’mosquito fever’’, three-day fever or “papatacci fever”. it is transmitted by phlebotomus papatasi , starts with acute onset of high fever, and lasts for three days. we present first cases in a different district of turkey with the clinical findings of fever, myalgia-arthralgia, headache, gastrointestin...

in order to distinguish between benign and malignant types of pigmented skin lesions, computerized procedures have been developed for images taken by different equipment that the most available one of them is conventional digital cameras. in this research, a new procedure to detect malignant melanoma from benign pigmented lesions using macroscopic images is presented. the images are taken by co...

In this interesting paper, the authors have successfully quantified the predictive capabilities of the single-blind, Phase IIa photosensitivity model. Most importantly, their conclusion stresses that potential AEDs showing suppression of the pathological generalized epileptogenic reaction to Intermittent Photic Stimulation (IPS) also show efficacy in phase III double-blind placebo-controlled AE...

Photosensitivity, photosensitive seizures, and photosensitive epilepsy are discussed. The International League against Epilepsy has suggested the term "visual-sensitive" replace "photosensitive". Visual-sensitive seizures may be more common than is realized. A classification for visual-sensitive epilepsies is presented. Chromosomal and DNA testing may help to refine the classification further. ...

In our previous study, photoprovocation induced lupus erythematosus (LE) and polymorphous light eruption-like lesions in photosensitive LE patients. In this new study we examined the expression of ICAM-1, VCAM-1 and E-selectin, in early lesions in particular. A total of 32 patients with cutaneous LE, 25 with "classic" discoid LE, and 7 with systemic LE, including 3 patients with subacute cutane...