A novel AIE poly(phosphoramidate) was synthesized through an ester ammonolysis reaction by using triethyl phosphate and diamines. Surprisingly, the obtained polymer is sensitive to Cu 2+ can be used as in situ visual detection agent for .

The initial stages of fermentation of glycogen to lactic acid in muscle have been investigated only recently. It was shown (1, 2) that the glycolytic reactions are initiated by the formation of glucose-l-phosphoric acid from glycogen and inorganic phosphate, an enzymatic process in which adenylic acid acts as coenzyme. The glucose-l-phosphoric acid (l-ester) is converted to glucose-6phosphoric ...

Sedoheptulose-7-phosphate, originally identified as a product of photosynthesis in algae and higher plants (3), has been shown to arise by the action of transketolase on pentose phosphate (4, 5). This reaction occurs in a wide variety of animal (5, 6), plant (5, 7), and microbial cells (8-lo), and evidence has been obtained that the heptulose ester is an intermediate in the formation of hexose ...

The serine protease inhibitors diethyl p-nitrophenyl phosphate and phenylmethylsulfonyl fluoride (chemical modifiers of serine residue) and N-acetyl-l-tryptophan ethyl ester (competitive inhibitor of chymotryptic protease) inhibited 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (AGEPC; platelet-activating factor)-induced platelet aggregation and secretion. The inhibition was dependent on the p...

The externally controlled cleavage of covalently linked prodrugs, proteins, or solid-phase formulation vehicles offers potential advantages for controlled drug or gene delivery. A series of o-nitrobenzyl ester compounds (1-8) were synthesized to allow a systematic study of photolability. The o-nitrobenzyl ester was strictly required for photolability, while imido esters were not photolabile. Th...

Chapter 1. Magnesium-dependent phosphate ester processing enzymes frequently employ a carboxylate-bridged dimetallic unit in their active sites. Biomimetic modelling chemistry of these magnesium centers has not been investigated previously. An brief introduction of the enzyme systems is presented, along with the focus of the present work. Chapter 2. Several dimagnesium(II) complexes were synthe...