OBJECTIVE This study was designed to test the accuracy of capillary ketonemia for diagnosis of ketosis after interruption of insulin infusion. RESEARCH DESIGN AND METHODS A total of 18 patients with type 1 diabetes treated by external pump were studied during pump stop for 5 h. Plasma and capillary ketonemia and ketonuria were determined every hour from 7:00 A.M. (time 0 min = T0) to 12:00 P....

BACKGROUND AND OBJECTIVE Diabetic ketoacidosis (DKA) is the most severe acute metabolic complication of type 1 diabetes mellitus. Insulin treatment is commonly guided by plasma glucose levels and changes in venous blood gases, while β-hydroxibutyrate (BHB) levels are rarely measured. The study objective was to evaluate the value of capillary BHB monitoring in the course and resolution of DKA. ...

The significance of acetone bodies in the urine subsequent to surgical operations has long been the cause of controversy and is not as yet settled. It is now well recognised that ketone bodies are not necessarily associated with acidosis. Although a ketosis usually accompanies an acidosis, the reverse is by no means the case. Despite the fact that a true acidosisa lepletion of the alkali reserv...

Variations in the concentration of taurine have been noted by several workers during chromatographic investigation of urinary amino-acids (Kay and Entenman, 1954; Souchon and Grunau, 1952; Ishihara, Komori, and lida, 1951 ; Nardi, 1954; Beerstecher, Sutton, Berry, Brown, Reed, Rich, Berry, and Williams, 1950). Taurine is present in high concentration in liver (Tallan, 1954), and it is in the li...

OBJECTIVE To evaluate rumen transfaunation after surgical correction of left-sided displacement of the abomasum (LDA) in cows. DESIGN Prospective clinical trial. ANIMALS 20 multiparous cows with LDA. PROCEDURES Cows with LDA were treated surgically (day 0). On days 0 (immediately after surgery) and 1, 10 cows each received 10 L of rumen fluid (transfaunated group) or 10 L of water (contro...

Herpes simplex virus infections have been previously reported in diabetic patients. This study therefore investigated the prevalence of Herpes simplex virus (HSV–1, 2) in patients attending a diabetic clinic of a medical centre in a community in southwest Nigeria. Three hundred and twenty (320) patients aged between 35 – 50 years were screened for fasting blood sugar (FBS); urine sugar (US), ur...

BACKGROUND The use of capillary blood 3-β-hydroxybutyrate (3HB) is a more precise method than urine ketones measurement for the diagnosis of diabetic ketoacidosis. Fasting ketonuria is common during normal pregnancy, while there is evidence that it is increased among pregnant women with Gestational Diabetes Mellitus (GDM) who are on a diet. 3HB levels have been related to impaired offspring psy...

The formation of ketone bodies and their excretion in the urine in albnormall amounts have for many years been problems of much interest to both physiologist and clinician. Much of our present knowledge of the subject has been gained from the study of carbohydrate metabolism in diabetes, where ketonuria in its classical formi is frequently observed. From this it has been established that an exc...