Mass cytometry is a novel platform for high-dimensional phenotypic and functional analysis of single cells. This system uses elemental metal isotopes conjugated to monoclonal antibodies to evaluate up to 42 parameters simultaneously on individual cells with minimal overlap between channels. The platform can be customized for analysis of both phenotypic and functional markers. Here, we will desc...

throughout the present study the effect of using markers close to genes affecting a trait, ascompared with the use of all the markers of a genome, and also the effect of on increase in thenumber of reference groups, on the accuracy of a genetic evaluation, was investigated. genomicevaluation was done using blup method. the results indicated that use of markers close to genesaffecting a trait an...

Genetic diversity among plants sprouted from seven year old clones of mulberry (Morus indica var. S36) was studied using molecular markers such as ISSR and RAPD. The clones showed significant variability in sex expression and the sprouting behavior. These changes were appeared after seven years of rigorous pruning and training (pruned once in every 3-4months). Genetic diversity analysis reveale...

Stochastic switching is an example of phenotypic bet hedging, where offspring can express a phenotype different from that of their parents. Phenotypic switching is well documented in viruses, yeast, and bacteria and has been extensively studied when the selection pressures vary through time. However, there has been little work on the evolution of phenotypic switching under both spatially and te...

This study reports the rates of phenotypic switching in strains of Candida albicans isolated from superficial and invasive infections. Of 19 invasive strains, 68% showed switching activity, often at very high rates, compared with only 28% of 40 strains isolated from superficial sites (P = 0.004).

Resistance gene analog polymorphism (RGAP) markers linked to Fusarium head blight resistance (FHB) and co-localize with Qfhs.ndsu-3BS were identified using F3 plants and F3:5 lines derived from a ‘Wangshuibai’ (resistant) / ‘Seri82’ (susceptible) cross. The mapping populations were genotyped using 50 degenerate primers designed based on the known R genes. Out of the 50 designed primer combinati...