Phenanthraquinone (PQ) is a component of diesel exhaust particles which inhibits nitric oxide synthase (NOS) activity by shunting electrons away from the normal catalytic pathway of the enzyme and which can oxidize proximal protein sulfhydryls. In the present study, we examined the possibility that PQ may also modify critical thiol residues on endothelial NOS (eNOS), leading to a disruption of ...

Purpose: To isolate and characterize chemical compounds of biological importance from the whole plant of Dendrobium hongdie. Methods: The whole plants of Dendrobium hongdie was extracted with ethanol (EtOH) and separated using silica gel, Sephadex LH-20 and MCI gel to isolate the pure compounds. Characterization of the isolated compounds was achieved using H and C nuclear magnetic resonance spe...

A new, convenient, efficient, and cost-effective one-pot synthesis of 1Hphenanthro[9,10]imidazol-2-yl from phenanthraquinone and aldehydes, using sulfuric acidimmobilized on silica as catalyst is described. The present methodology offers severaladvantages such as excellent yields, simple procedure, shorter reaction times, the use ofinexpensive reagents, easy recovery and eco-friendly. In additi...

a new, convenient, efficient, and cost-effective one-pot synthesis of 1hphenanthro[9,10]imidazol-2-yl from phenanthraquinone and aldehydes, using sulfuric acidimmobilized on silica as catalyst is described. the present methodology offers severaladvantages such as excellent yields, simple procedure, shorter reaction times, the use ofinexpensive reagents, easy recovery and eco-friendly. in additi...