Purpose: We had previously shown the MR compatibility of CZT based single photon detectors and associated nuclear data acquisition electronics [1]. The purpose of the present work was to study the feasibility a combined MRSPECT system operating inside a 4T MR system for dual-modality MR-SPECT imaging. The current investigation included a study of the effect of SPECT detector/collimator system o...

Introduction: Integration of single photon emission computed tomography (SPECT) and computed tomography (CT) scanners into SPECT/CT hybrid systems permit detection of coronary artery disease in myocardial perfusion imaging (MPI). Misregistration between CT and emission data can produce some errors in uptake value of SPECT images. The aim of this study was evaluate the influence...

  Introduction: Monte Carlo (MC) is the most common method for simulating virtual SPECT projections. It is useful for optimizing procedures, evaluating correction algorithms and more recently image reconstruction as a forward projector in iterative algorithms; however, the main drawback of MC is its long run time. We introduced a model based method considering the eff...

introduction: in this study the evaluation of a platelet-based maximum penalized likelihood estimation (mple) for denoising spect images was performed and compared with other denoising methods such as wavelets or butterworth filtration. platelet-based mple factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to poisson n...

objective(s): a novel iq-specttm method has become widely used in clinical studies. the present study compares the quality of myocardial perfusion images (mpi) acquired using the iq-specttm (iq-mode),conventional (180° apart: c-mode) and l-mode (90° apart: l-mode) systems. we assessed spatial resolution, image reproducibility and quantifiability using various physical phantoms. materials and me...

introduction:it is well-recognized that collimator-detector response (cdr) is the main image blurring factor in spect.  in this research, we compensated the images for cdr in molecular spect by using stir reconstruction framework. methods: to assess resolution recovery capability of the stir, a phantom containing five point sources along with a micro derenzo phantom were investigated. influence...

PURPOSE Brain single photon emission computed tomography (SPECT) imaging is an important clinical tool, with unique tracers for studying neurological diseases. Nowadays, most commercial SPECT systems are combined with x-ray computed tomography (CT) in so-called SPECT/CT systems to obtain an anatomical background for the functional information. However, while CT images have a high spatial resolu...

Introduction: In this study the evaluation of a Platelet-based Maximum Penalized Likelihood Estimation (MPLE) for denoising SPECT images was performed and compared with other denoising methods such as Wavelets or Butterworth filtration. Platelet-based MPLE factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to Poi...

OBJECTIVES Small animal imaging has recently been focused on basic nuclear medicine. We have designed and built a small animal SPECT imaging system using a semiconductor camera and a newly designed collimator. We assess the performance of this system for small object imaging. METHODS We employed an MGC 1500 (Acrorad Co.) camera including a CdTe semiconductor. The pixel size was 1.4 mm/pixel. ...

BACKGROUND A brain single-photon emission computed tomography (SPECT) system using cadmium telluride (CdTe) solid-state detectors was previously developed. This CdTe-SPECT system is suitable for simultaneous dual-radionuclide imaging due to its fine energy resolution (6.6 %). However, the problems of down-scatter and low-energy tail due to the spectral characteristics of a pixelated solid-state...