Acknowledgements I first want to say that it was a pleasure and great experience to have Oded as advisor. On one hand I had much liberty, but on the other hand Oded was very available to support and guide me during all Ph.D phases (and even thereafter for finding a job !). I hope to have learned from his particular way to look at science in a positive, fresh and ambitious way. I sincerily thank...

fruit waste extract was selected as the sole substrate for carotenoid production and the effect of parameters like ph, temperature and agitation have been studied. a two-step simple sequential strategy was employed for the optimization of carotenoid production by rhodotorula rubra. in the first step, one factor at a time was employed to evaluate the impact of ph on carotenoid production. the ou...

results escherichia coli phytase was expressed in p. pastoris under different cultivation conditions (post-induction temperature, methanol concentration, and post-induction ph). the optimized conditions by rsm using face centered central composite design were 1% (v/v) methanol, ph = 5.8, and 24.5°c. under the optimized conditions, appa was successfully expressed in p. pastoris and the maximum p...

objective(s):[p1]  this study highlights xylanase overproduction from bacillus mojavensis via uv mutagenesis and optimization of the production process. materials and methods:bacillus mojavenis ptcc 1723 underwent uv radiation. mutants’ primary screening was based on the enhanced hollow zone diameter/ colony diameter ration (h/c ratios) of the colonies in comparison with the wild strain on xyla...

BACKGROUND Production of alkaline protease from various bacterial strains using statistical methods is customary now-a-days. The present work is first attempt for the production optimization of a solvent stable thermoalkaline protease by a psychrotrophic Pseudomonas putida isolate using conventional, response surface methods, and fermentor level optimization. RESULTS The pre-screening medium ...

Determining the surface protonation behavior of natural adsorbents is essential to understand how they interact with their environments. ProtoFit is a tool for analysis of acid–base titration data and optimization of surface protonation models. The program offers a number of useful features including: (1) enables visualization of adsorbent buffering behavior; (2) uses an optimization approach i...

Biogas production rate is an important criterion for the entire biogas production process. In the present study the biogas production rate was evaluated using more than 30 process variables measured at an agricultural biogas plant in Germany during two months. The measured variables include the chemical measurements (such as pH, dried matter, amount of organic acids), energy supply specificatio...

Progressive Hedging (PH) is a well-known algorithm for solving multi-stage stochastic convex optimization problems. Most previous extensions of PH for stochastic mixed-integer programs have been implemented without convergence guarantees. In this paper, we present a new framework that shows how PH can be utilized while guaranteeing convergence to globally optimal solutions of stochastic mixed-i...

In this work, the pH neutralization process is described by a neural network Wiener (NNW) model. A nonlinear Model Predictive Control (NMPC) is established for the considered process. The main difficulty that can be encountered in NMPC is solving the optimization problem at each sampling time to determine an optimal solution in finite time. The aim of this paper is the use of global optimizatio...