In this paper, we review novel techniques in the emerging field of spatiotemporal 4D PET imaging. We will discuss existing limitations in conventional dynamic PET imaging which involves independent reconstruction of dynamic PET datasets. Various approaches that seek to attempt some or all of these limitations are reviewed in this work, including techniques that util...

  The advent of dual-modality PET/CT imaging has revolutionized the practice of clinical oncology, cardiology and neurology by improving lesions localization and the possibility of accurate quantitative analysis. In addition, the use of CT images for CT-based attenuation correction (CTAC) allows to decrease the overall scanning time and to create a noise-free attenuat...

FDG PET CT scan is considered to be a sensitive tool to detect skeletal metastasis in known malignancies. However, it’s high sensitivity and low specificity may account for false positive diagnosis in cases of trauma, infection, inflammation and other benign conditions. Skeletal hemangioma is one of the common benign conditions which are typically ametabolic on FDG PET CT with no uptake on bone...

This paper intends to compare the abilities of the two major imaging modalities in nuclear medicine imaging: Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT). The motivations are many-fold: (i) To gain a better understanding of the strengths and limitations of the two imaging modalities in the context of recent and ongoing developments in hardware ...

PET (positron emission tomography) is a powerful imaging technique that can provide quantitative information on the distribution of positron emitter labeled radiopharmaceuticals (PET radiopharmaceuticals) in the body. Positrons (ß+) are positively charged beta particles. They are emitted when the atom is proton rich. A positron has only a transient existence. After losing all of its kinetic ene...

PET (positron emission tomography) is a powerful imaging technique that can provide quantitative information on the distribution of positron emitter labeled radiopharmaceuticals (PET radiopharmaceuticals) in the body. Positrons (ß+) are positively charged beta particles. They are emitted when the atom is proton rich. A positron has only a transient existence. After losing all of its kinetic ene...

Objective(s): 18F-fluciclovine (trans-1-amino-3-[18F] fluorocyclobutanecarboxylic acid, [FACBC]) is an artificial amino acid radiotracer used for positron emission tomography (PET) studies, which is metabolically stable in vivo and has a long half-life. It has already been shown that FACBC-PET is useful for glioma imaging. However, there have been no reports evaluating the efficiency of FACBC-P...

this paper intends to compare the abilities of the two major imaging modalities in nuclear medicine imaging: positron emission tomography (pet) and single photon emission computed tomography (spect). the motivations are many-fold: (i) to gain a better understanding of the strengths and limitations of the two imaging modalities in the context of recent and ongoing developments in hardware and so...

A 65 year old male with metastatic colorectal cancer (mCRC) in the liver was referred for selective internal radionuclide therapy (SIRT) following a history of extensive systemic chemotherapy. 90Y PET imaging was performed immediately after treatment and used to confirm lesion targeting and measure individual lesion absorbed doses. Lesion dosimetry was highly predictive of eventual response in ...

Introduction: Accurate staging plays an important role in management of patients with prostate cancer especially in high-risk group. Today, [68Ga]Ga-PSMA-11 PET/CT should be considered as the preferred imaging tool for treatment planning and initial staging of the disease. Methods: A total number of 628 patients with prostate cancer referred to...