Peripheral arterial disease (intermittent claudication) is typically age-dependent and is not uncommon after the age of about 65 years. Exercise training in peripheral arterial disease leads to an increased walking distance and reduced pain, and likely also a slowed progression of the disease process itself. For optimal effect, the exercise should be carried out as walk training, preferably int...

• Objective: To review the evaluation and treatment of patients with peripheral arterial occlusive disease

Background. Peripheral arterial disease (PAD) is associated with an impairment in exercise performance and muscle function that is not fully explained by the reduced leg blood flow during exercise. This study characterized the effects of PAD on muscle function, histology, and metabolism. Methods and Results. Twenty-six patients with PAD and six age-matched control subjects were studied. Ten of ...

Peripheral arterial disease (PAD) affects 15% of the Australian population and is a powerful and serious predictor of cardiovascular mortality yet continues to be under-recognised and undertreated. Diagnosis is simple and management is centred upon symptom relief and risk minimisation. While novel and specialised therapies play a role, the bulk of management is approachable and feasible. In thi...