Objective: Asphyxia  is  a  major  cause  of  acute  mortality  and  chronic  neurologic  disability  in  neonates. We sought to  define  the  predictive  values  of  serum  concentrations  of  interleukin-1β  in  newborns  with perinatal asphyxia to see if there is a relation between interleukin-1β (IL-1β) levels to the short term neurological deficit.  Methods: This was a prospective (case-co...

perinatal asphyxia using the cardiac biomarkers cTnI and brain natriuretic peptide (BNP). Troponin T and I are sensitive markers of myocardial injury following a perinatal hypoxic-ischaemia insult. BNP is a marker of ventricular wall stress secondary to myocardial dysfunction [8] . cTnI and BNP were collected before the start of hypothermia, at 24 and 48 h after birth, and after rewarming. BNP ...

OBJECTIVE To assess the annual burden of early neonatal deaths associated with perinatal asphyxia in infants weighing ≥2500g in Brazil from 2005 to 2010. METHODS The population study enrolled all live births of infants with birth weight ≥2500g and without malformations who died up to six days after birth with perinatal asphyxia, defined as intrauterine hypoxia, asphyxia at birth, or meconium ...

INTRODUCTION Perinatal asphyxia is one of the main causes of perinatal mortality and morbidity worldwide and it generates high costs for health systems; however, it has modifiable risk factors. OBJECTIVE To identify the risk factors associated with the development of perinatal asphyxia in newborns at Hospital Universitario del Valle, Cali, Colombia. MATERIALS AND METHODS Incident cases and ...

BACKGROUND Perinatal asphyxia can cause serious illness or death. By taking steps in the «latent phase», which occurs 6-24 hours after the hypoxic event, the neurological damage caused by perinatal asphyxia can be limited. We wish to present a selection of such measures that are either established treatment today or that appear promising. METHOD We searched in the Medline and Cochrane Library...

Background: Perinatal asphyxia is a common cause of infant morbidity and mortality and long-term neurological disabilities. Due to the high costs of admission, a large proportion of births and neonatal deaths occur in non-hospital settings. This study aimed to evaluate the incidence rate of perinatal asphyxia before and after the implementation of the health improvement program. Methods: This d...

BACKGROUND Pre- and perinatal adversities may increase the risk for schizophrenia and bipolar disorder. Hypoxia-related obstetric complications (OCs) are associated with brain anatomical abnormalities in schizophrenia, but their association with brain anatomy variation in bipolar disorder is unknown. METHOD Magnetic resonance imaging brain scans, clinical examinations and data from the Medica...

Perinatal asphyxia during delivery produces long-term disability and represents a major problem in neonatal and pediatric care. Numerous neuroprotective approaches have been described to decrease the effects of perinatal asphyxia. Enriched environment is a popular strategy to counteract nervous system injuries. The aim of the present study was to investigate whether enriched environment is able...

background: perinatal asphyxia is a common cause of infant morbidity and mortality and long-term neurological disabilities. due to the high costs of admission, a large proportion of births and neonatal deaths occur in non-hospital settings. this study aimed to evaluate the incidence rate of perinatal asphyxia before and after the implementation of the health improvement program. methods: this d...

delivered safely. Perinatal death audits that evaluate both cause of death and potential for preventability are crucial to reduce preventable mortality. Finally, availability of sufficient staff and appropriate equipment to handle obstetric emergencies is crucial. Most important is the recognition that in order to reduce neonatal death and disability from intrapartum asphyxia, prevention and tr...