Myocardial perfusion MRI is acquired with a T1-weighted dynamic MRI sequence. Fully quantitative analysis of myocardial perfusion MRI allows the absolute quantification of myocardial blood flow (MBF) through the use of complex mathematical modeling. There are essentially two main methods for quantification of absolute MBF: the linear time-invariant model and the compartment model. Maximized con...

BACKGROUND To simplify development of normal limits for myocardial perfusion SPECT (MPS), we implemented a quantification scheme in which normal limits are derived without visual scoring of abnormal scans or optimization of regional thresholds. METHODS AND RESULTS Normal limits were derived from same-day TI-201 rest/Tc-99m-sestamibi stress scans of male (n = 40) and female (n = 40) low-likeli...

Various liver diseases lead to significant alterations of the hepatic microcirculation. Therefore, quantification of hepatic perfusion has the potential to improve the assessment and management of liver diseases. Most methods used to quantify liver perfusion are invasive or controversial. This paper describes and validates a non-invasive method for the quantification of liver perfusion using co...

OBJECTIVES The purpose of this study was to compare the assessment of myocardial perfusion by myocardial parametric quantification (MPQ) with technetium-99m sestamibi single-photon emission computed tomographic (SPECT) imaging in humans. BACKGROUND Accurate visual interpretation of myocardial contrast echocardiographic (MCE) images is qualitative and requires considerable experience. Current ...

Background Myocardial ischaemic burden is an important marker of outcome in stable ischaemic heart disease with a 10% ischaemic burden suggested as a clinically relevant threshold for revascularisation. Standard CMR stress perfusion imaging utilises 3 short axis slices, each acquired in different phases of the cardiac cycle. Recently proposed 3D myocardial perfusion CMR allows the entire myocar...

Abstract is NOT available.

Introduction Quantification of myocardial perfusion from cardiac magnetic resonance (CMR) images relies on manual tracing of myocardial regions of interest (ROIs) and their repositioning frame-by-frame throughout the contrast-enhanced image sequence. Additionally, out-of-plane motion due to patient’s respiration frequently requires that myocardial ROIs to be redrawn.This tedious and potentially...