RATIONALE Data on nonvitamin K antagonist oral anticoagulant being used for the treatment of LAA thrombi are limited only in nonvalvular atrial fibrillation. There are no data on the antithrombotic efficacy and safety of nonvitamin K antagonist oral anticoagulant in the resolution of left atrial appendage (LAA) thrombi in patients with rheumatic mitral stenosis. PATIENT CONCERNS A 49-year-old...

INTRODUCTION Mitral stenosis (MS) causes structural and functional abnormalities of the left atrium (LA) and left atrial appendage (LAA), and studies show that LAA performance improves within a short time after percutaneous transvenous mitral commissurotomy (PTMC). This study aimed to investigate the effects of PTMC on left atrial function by transesophageal echocardiography (TEE). METHODS We...

To cite: Hirapur IS, Rajendran R, Kolhari VB, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013010391 DESCRIPTION Rheumatic heart disease (RHD) is still highly prevalent in developing countries and accounts for sizeable cardiovascular morbidity. The mitral valve is the most commonly involved valve. Since its introduction by Inoue et al in 1984 as an alte...

Percutaneous transvenous mitral commissurotomy was performed in 106 consecutive patients. Significant symptomatic improvement was achieved in 97 patients (92%). Mean left atrial pressure decreased (from 18 +/- 8 to 11 +/- 8 mm Hg, p less than 0.00001), mean mitral diastolic pressure gradient decreased (from 12 +/- 7 to 7 +/- 6 mm Hg, p less than 0.00001), and mitral valve area increased (from 1...

the left ventricular aneurysm is one of the most significant complications of myocardial infarction and is defined as the expansion of the ventricular wall. the coronary artery aneurysm is characterized by an abnormal dilation of the localized portion of the coronary artery, and its main cause is atherosclerosis. we herein report an unusual case of coronary artery and left ventricular aneurysms...

Background. Improvement of exertional dyspnea occurs immediately after percutaneous transvenous mitral commissurotomy (PTMC), but the pathophysiological basis for this early symptomatic improvement has not been elucidated. Methods and Results. Exercise hemodynamic measurement and exercise ventilatory measurement with arterial blood gas analysis were performed in 21 patients aged 50.4+9.5 years ...

Background: Apelin is an endogenous peptide with positive inotropic property secreted by the heart besides other tissues. Plasma apelin levels are altered in chronic heart failure with left ventricular dysfunction. However, the effect of left atrial hemodynamic overload on plasma apelin levels in mitral stenosis (MS) is unknown. In this observational study, we estimated plasma apelin level in M...