In our laboratories some 200 compounds, including phenylacetic acid derivatives, have been studied as possible precursors for new penicillins, and several of these appeared to give rise to new penicillins. In this report, five new penicillins, four of which were obtained in crystalline form, are described and their production, isolation, and characterization discussed. The methods employed in o...

Abstract Objectives Data on consumption of penicillins in the community were collected from 30 EU/European Economic Area (EEA) countries over two decades. This article reviews temporal trends, seasonal variation, presence change-points and changes composition main subgroups penicillins. Methods For period 1997–2017, data penicillins, i.e. β-lactam antibacterials, (ATC group J01C), aggregated at...