We evaluated the in vitro antiproliferative and apoptotic potential of the ethyl acetate extract (EAE) of Peltophorum africanum, a member of the family Fabaceae (Sond) in order to validate its pharmacological use. Antiproliferation of human breast (MCF-7), colon (HT-29) and cervical (HeLa) cancer cell lines by EAE was investigated using the Cell Titer-Blue viability assay and the mechanism of a...

There is ample scientific and empirical evidence supporting the use of plant-derived antioxidants for the control of neurodegenerative disorders. Antioxidants may have neuroprotective (preventing apoptosis) and neuroregenerative roles, by reducing or reversing cellular damage and by slowing progression of neuronal cell loss. Although demand for phytotherapeutic agents is growing, there is need ...

The monophyly of the Peltophorum group, one of nine informal groups recognized by Polhill in the Caesalpinieae, was tested using sequence data from the trnL-F, rbcL, and rps16 regions of the chloroplast genome. Exemplars were included from all 16 genera of the Peltophorum group, and from 15 genera representing seven of the other eight informal groups in the tribe. The data were analyzed separat...

Plants provide long-term and sustainable solutions to mitigate particulate matter (PM) pollution in urban environments. We evaluated total, fine, coarse large particle trapping abilities of an equal number common trees (Carica papaya, Citrus limon, Moringa oleifera, Ozoroa paniculosa, Peltophorum africanum, Psidium guajava) herbaceous species (Argemone ochroleuca, Catharanthus roseus, Gomphocar...

We evaluated the in-vitro antiproliferative and apoptotic potential of the ethyl acetate extract (EAE) of Peltophorum africanum, a member of the family Fabaceae (Sond) in order to validate its pharmacological use. Antiproliferation of human breast (MCF-7), colon (HT-29) and cervical (HeLa) cancer cell lines by EAE was investigated using the Cell Titer-Blue viability assay and the mechanism of a...

We assessed the in vitro antimicrobial activity of Peltophorum africanum by means of the agar well and macrodilution methods. The toxicity on a normal human liver cell (Chang liver cell) was determined using the CellTiter-Blue cell viability assay, and the compounds contained in the fractions were identified using GC-MS. Zone diameter of inhibition of the extract ranged from 12.5 ± 0.7  to  32 ...

M a i n r e s u l t s 18 RCTs (1562 patients) met the selection criteria. Comparisons included P. africanum extract with placebo (13 RCTs), P. africanum extract with an anti-inflammatory drug (2 RCTs), P. africanum extract with another herbal agent (1 RCT), different daily doses of P. africanum extract (1 RCT), and 2 different doses of P. africanum extract in combination with another herbal ext...