In studies of intestinal absorption non-absorbed markers are used to indicate changes in volume of the contents of the bowel. Polyethylene glycol 4000 (PEG 4000), a popular marker, has been shown to fulfil the criteria of a volume indicator (Hyden, 1956b; Jacobson, Bondy, Broitman, and Fordtran, 1963; Maddrey, Serebro, Marcus, and Iber, 1967; Shields, Harris, and Davies, 1968). The concentratio...

The objective of the present work was to improve the dissolution properties of the poorly water-soluble drug meloxicam by preparing solid dispersions with hydroxyethyl cellulose (HEC), mannitol and polyethylene glycol (PEG) 4000 and to develop a dosage form for geriatric population. Differential scanning calorimetry, X-ray diffractometry, Fourier transform infrared spectroscopy and scanning ele...

PURPOSE To evaluate the correlation between colon transit time (CTT) test value and initial maintenance dose of polyethylene glycol (PEG) 4000 or lactulose. METHODS Of 415 children with chronic functional constipation, 190 were enrolled based on exclusion criteria using the CTT test, defecation diary, and clinical chart. The CTT test was performed with prior disimpaction. The laxative dose fo...

Extraction of laccase produced by L. polychrous in an aqueous two-phase system, composed of polyethylene glycol and phosphate salt at pH 7.0 and 25C was investigated. The effect of PEG molecular weight, PEG concentration and phosphate concentration was determined. Laccase preferentially partitioned to the top phase. Good extraction of laccase to the top phase was observed with PEG 4000. The opt...

EVALUATION OF PEG 4000 SOLUTION STABILITY IN DIFFERENT TEMPERATURES AND ENVIRONMENTAL CONDITIONS OVER THE TWELVE MONTHS

The present work investigates the feasibility of the design of an enteric coated microporous osmotic pump tablet (ECMOPT) to prolong the drug release of an antipsychotic drug, quetiapine fumarate (QTF). The ECMOPT consisted of an osmotic core coated with a microporous membrane (MPM) made up of cellulose acetate and PEG 4000 as in situ micropore former. The effect of formulation variables such a...

Solid Dispersions were prepared by solvent evaporation technique using microcrystalline cellulose, PEG 4000, PEG 6000, PVP-K30 and Gelucire 50/13. Further objective of the project was to develop fast release surface solid dispersion of glibenclamide and compressed at low pressure to form fast-melting pharmaceutical tablet. In this study, we used sodium starch glycolate for mouth dissolving natu...

Abstract: All production activities will eventually produce waste, especially liquid waste. The nitrate ion (NO3-) is one of the substances in waste that can have a significant impact on water systems and human health. Several methods be used to treat contained water, such as adsorption, phytoremediation, wetland treatment. One its was adsorption. silica modified with polymer due huge carbon ch...

this study investigated the applicability of polyethylene glycol (peg-4000) coated fe3o4 magnetic nanoparticles for the selective removal of toxic pb (ii) ion from wastewater. the fe3o4 magnetic nanoparticles of 24 nm were synthesized using a coprecipitation method and characterized by scanning electron microscopy (sem), vibratingsample magnetometer (vsm), and x-ray diffraction (xrd). sem image...