BACKGROUND The aims of this study are to investigate the difference between the diaphragm thickness at end expiration and the thickness at total lung capacity (TLC), and to examine differences in inspiratory muscle function between stroke patients and healthy individuals. MATERIAL AND METHODS Forty-five stroke patients and 49 healthy volunteers were included in this study. Diaphragm thickness w...

The aerodynamic particle size distribution (APSD) and dose emission characteristics of indacaterol Breezhaler have been measured using ex-vivo methodology altering original COPD inhalation manoeuvre profiles to investigate the influence inspiratory parameters namely, peak flow (PIF), acceleration rate (ACIM) inhaled volume (Vin) by keeping two fixed varying other one. All had an impact on emiss...

The ability of the noninvasive methods forced oscillation technique (Rosc), spirometry and flow-volume curves to detect and quantify laryngeal obstruction, using assessment of orolaryngeal (upper) airway resistance (Rol) as reference, was compared in 55 patients with various laryngeal diseases. Statistical analysis was performed by means of sensitivity/specificity, simple regression, stepwise r...

OBJECTIVE The Technosphere Insulin (TI) inhalation system comprises TI powder premetered into unit dose cartridges and the patient-friendly, reusable, breath-powered MedTone inhaler. This high-resistance system uses a patient's inspiratory effort to effect TI powder de-agglomeration and promote subsequent deep-lung delivery. This study reports on flow and pressure data achieved by patients with...

BACKGROUND We compared spontaneous and positive-pressure ventilation in patients undergoing general anaesthesia for the treatment of extrathoracic, intralumenal laryngotracheal stenosis to assess the best method of ventilation in this patient group. METHODS Records of 30 patients with laryngotracheal stenosis, but not with a tracheostomy, undergoing lumen-restoring surgery were prospectively ...

INTRODUCTION Drug inhalation via a dry-powder inhaler (DPI) is a convenient, time efficient alternative to nebulizers in the treatment of cystic fibrosis (CF). Efficient drug administration via DPIs depends on the device resistance and adequate (≥ 45L/min) inspiratory flows and volumes generated by individuals. Dry-powder mannitol is delivered using a RS01 breath-actuated device developed by Pl...

conclusions negative pressure inspiration is significantly impaired by an unstable chest wall. restoring mechanical stability of the fractured ribs improves respiratory outcomes similar to baseline values. results a wide variation in the mean inspiratory volumes and peak flows were measured between specimens; however, the effect of a flail chest wall and the subsequent internal fixation of the ...

The output and size distribution of aerosols from dry powder inhalers are dependent on the flow rate through the device. Therefore, in an in vivo study, we examined the flow-dependency of the effect of formoterol when delivered from a dry powder inhaler, the Aerolizer, in a flow range relevant to schoolchildren. In a preliminary study comprising 126 asthmatic children aged 3-10 yrs, the relatio...

The efficacy of partial arytenoidectomy was assessed in 6 Standardbred horses, with surgically induced laryngeal hemiplegia, at rest (Period A) and during exercise at speeds corresponding to maximum heart rate (Period C) and 75% of maximum heart rate (Period B). Peak expiratory and inspiratory airflow rate (PEF and PIF), and expiratory and inspiratory transupper airway pressure (PUE and PUI) we...

Objective: Effect of peppermint on exercise performance was previously investigated but equivocal findings exist. This study aimed to investigate the effects of peppermint ingestion on the physiological parameters and exercise performance after 5 min and 1 h. Materials and Methods: Thirty healthy male university students were randomly divided into experimental (n=15) and control (n=15) groups. ...