adenosine acts as neuromodulator in the brain, which its involvement in a wide range of brain processes and diseases has been studied, such as epilepsy, sleep, anxiety, panic disorder, alzheimer’s disease, parkinson’s disease and schizophrenia. adenosine receptors have been detected: a1r, a2ar (a2ar), a2br, and a3r. a1r and a2r inhibit camp production, while a2ar and a2br stimulate camp product...

JAMES RYAN, Expressive Intelligence Studio, University of California, Santa Cruz ERIC KALTMAN, Expressive Intelligence Studio, University of California, Santa Cruz ANDREW MAX FISHER, Games and Playable Media, University of California, Santa Cruz TAYLOR OWEN-MILNER, 2K Games, Novato, California MICHAEL MATEAS, Expressive Intelligence Studio, University of California, Santa Cruz NOAH WARDRIP-FRUI...

Studio-based teaching focuses on problem/project work and experimentation in a hands-on studio environment. Traditionally found in the arts and architecture, it is now being used in other fields such as Instructional Technology and the sciences. The first link below describes the history and rationale of studio-based teaching. Subsequent links provide information on studio teaching in a variety...

Network-based approaches are powerful and beneficial tools to study complex systems in their entirety, elucidating the essential factors that turn the multitude of individual elements into a functional system. In this study we used critical network topology descriptors and guilt-by-association rule to explore and understand the significant molecular players, drug targets and underlying biologic...

the objective of this study was to observe the apoptosis-inducing effect and mechanism of baicalin on human cervical cancer hela cells. the inhibitory effect of baicalin on the growth of hela cells was measured by mtt assay, and cell proliferation and migration was analyzed by cell scratch assay. morphological changes of apoptotic cells were viewed by the light microscope and electron microscop...

Carthamus tinctorius L. (Honghua, HH) is an herbal medicine and functional food widely used to treat chronic liver diseases, including fibrosis. By using network pharmacology molecular docking experiments, the present study aims determine bioactive components, potential targets, mechanisms of HH for treating The components were screened from Traditional Chinese Medicine Systems Pharmacology Dat...

The architectural curriculum has been based on the design studio class model which focuses on learning by doing and all processes and procedures of problem solving are transmitting trough lectures and critique sessions. The tutorial system in design studio classes is same as masterApprentice. So students learn during a communication between students and teachers and also between students. By th...

good sound and good value, properties they share with a number of other Canadian makes who have taken advantage of Canada’s National Research Council facilities in Ottawa. In fact, the first components I bought specifically for what is now my multichannel system were Paradigm Esprit BP speakers, which had impressed me at a Stereophile show. When I took the step into multichannel and found that ...

Aim of this paper is to search and find ways and methods of constructivism teaching and learning ideas inteaching the architectural design studio. The objective is to extract all the positive things constructivism has to offer the architectural design studio for efficient teaching and effective learning. Although there are similarities in the curricula of training architects all over the world,...